About ICS

Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.

Mouton-Liger F(1), Sahún I(2), Collin T(3), Lopes Pereira P(4), Masini D(2), Thomas S(1), Paly E(1), Luilier S(5), Même S(6), Jouhault Q(1), Bennaï S(1), Beloeil JC(6), Bizot JC(5), Hérault Y(7), Dierssen M(2), Créau N(8).
Neurobiol Dis 2014 Mar;63():92-106

View on PubMed

Generation and Use of Transgenic Mice in Drug Discovery

Guillaume Pavlovic, Véronique Brault, Tania Sorg andYann Hérault
Methods And Principles In Medicinal Chemistry: In Vivo Models For Drug Discovery 2014 11 AUG 2014;62(part 6):131-148

View on PubMed

Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L mice.

Lopez-Delisle L(1), Pierre-Eugène C, Bloch-Gallego E, Birling MC, Duband JL, Durand E, Bourgeois T, Matrot B, Sorg T, Huerre M, Meziane H, Roux MJ, Champy MF, Gallego J, Delattre O, Janoueix-Lerosey I.
Oncotarget 2014 May 15;5(9):2703-13

View on PubMed

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies.

Karp NA(1), Speak AO(1), White JK(1), Adams DJ(1), Hrabé de Angelis M(2), Hérault Y(3), Mott RF(4).
Plos One 2014 Oct 24;9(10):e111239

View on PubMed

Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?

Koutseff A, Mittelhaeuser C, Essabri K, Auwerx J, Meziane H.
Brain Res 2014 Jan 13;1542():32-40

View on PubMed

In Vivo 9.4T MRI and1H MRS for Evaluation of Brain Structural and Metabolic Changes in the Ts65Dn Mouse Model for Down Syndrome

S. Même1*, N. Joudiou1, N. Yousfi1, F. Szeremeta1, P. Lopes-Pereira2, J. C. Beloeil1, Y. Herault2,3,4, W. Même1
World Journal Of Neuroscience 2014 2014;4():152-163

Modeling Copy Number Variations in the Mouse

Yann Hérault, Arnaud Duchon, Damien Maréchal, Véronique Brault.
Advances In Genome Sciences, Keeping Up With Genome Sequence And Expression 2014 ;3():3-32

View on PubMed

Old spontaneously hypertensive rats gather together typical features of human chronic left-ventricular dysfunction with preserved ejection fraction.

Marzak H(1), Ayme-Dietrich E, Lawson R, Mokni W, Combe R, Becker J, Fertak LE, Champy MF, Monassier L.
J Hypertens 2014 Jun;32(6):1307-16

View on PubMed

Proteomic survey reveals altered energetic patterns and metabolic failure prior to retinal degeneration.

Griciuc A(1), Roux MJ, Merl J, Giangrande A, Hauck SM, Aron L, Ueffing M.
J Neurosci 2014 Feb 19;34(8):2797-812

View on PubMed

Regulator of G-protein signaling 18 controls both platelet generation and function.

Delesque-Touchard N(1), Pendaries C(1), Volle-Challier C(1), Millet L(1), Salel V(1), Hervé C(1), Pflieger AM(1), Berthou-Soulie L(2), Prades C(2), Sorg T(3), Herbert JM(1), Savi P(1), Bono F(1).
Plos One 2014 Nov 18;9(11):e113215

View on PubMed

Rfx6 maintains the functional identity of adult pancreatic beta cells.

Piccand J(1), Strasser P(1), Hodson DJ(2), Meunier A(1), Ye T(1), Keime C(1), Birling MC(3), Rutter GA(2), Gradwohl G(4).
Cell Rep 2014 Dec 24;9(6):2219-32

View on PubMed

Skin progenitor cells contribute to bleomycin-induced skin fibrosis.

Liu S(1), Herault Y, Pavlovic G, Leask A.
Arthritis Rheumatol 2014 Mar;66(3):707-13

View on PubMed

Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.

Clar J(1), Gri B(1), Calderaro J(2), Birling MC(3), Hérault Y(3), Smit GP(4), Mithieux G(1), Rajas F(1).
Kidney Int 2014 Oct;86(4):747-56

View on PubMed