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A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse.

Daubeuf F(1)(2), Becker J(3), Aguilar-Pimentel JA(4), Ebel C(5), Hrabe de Angelis M(4), Herault Y(3)(5)(6)(7)(8), Frossard N(1)(2).
Curr Protoc Mouse Biol 2017 Jun 19;7(2):88-99

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A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

Bowl MR(1), Simon MM(1), Ingham NJ(2)(3), Greenaway S(1), Santos L(1), Cater H(1), Taylor S(1), Mason J(4), Kurbatova N(4), Pearson S(3), Bower LR(5), Clary DA(5), Meziane H(6), Reilly P(6), Minowa O(7), Kelsey L(8)(9)(10); International Mouse Phenotyping Consortium, Tocchini-Valentini GP(11), Gao X(12), Bradley A(3), Skarnes WC(3), Moore M(13), Beaudet AL(14), Justice MJ(8)(9)(10)(14), Seavitt J(14), Dickinson ME(15), Wurst W(16), de Angelis MH(17), Herault Y(6)(18)(19)(20), Wakana S(7), Nutter LMJ(8)(9)(10), Flenniken AM(8)(9)(10), McKerlie C(8)(9)(10), Murray SA(21), Svenson KL(21), Braun RE(21), West DB(22), Lloyd KCK(5), Adams DJ(3), White J(3), Karp N(3), Flicek P(4), Smedley D(23), Meehan TF(4), Parkinson HE(4), Teboul LM(1), Wells S(1), Steel KP(2)(3), Mallon AM(1), Brown SDM(24).
Nat Commun 2017 Oct 12;8(1):886

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Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.

Wendling O(1), Champy MF(1), Jaubert S(2), Pavlovic G(1), Dubos A(1)(3)(4)(5)(6), Lindner L(1), Jacobs H(1), Mark M(1)(3)(4)(5)(6), Combe R(1), Da Cruz IG(1), Luche H(6), Mudgett JS(7), Rosahl T(7), Sorg T(1), Malissen M(2), Reilly PT(1), Herault Y(8)(9)(10)(11)(12).
Sci Rep 2017 Aug 29;7(1):9618

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Comparing ataxias with oculomotor apraxia: a multimodal study of AOA1, AOA2 and AT focusing on video-oculography and alpha-fetoprotein.

Mariani LL(1)(2), Rivaud-Pechoux S(3), Charles P(1), Ewenczyk C(1), Meneret A(2)(3), Monga BB(4), Fleury MC(5)(6)(7), Hainque E(8)(9)(10), Maisonobe T(11), Degos B(2), Echaniz-Laguna A(5)(12), Renaud M(5)(6)(7), Wirth T(5), Grabli D(2)(9), Brice A(1)(9)(10), Vidailhet M(2)(9)(10), Stoppa-Lyonnet D(13)(14), Dubois-d'Enghien C(13), Le Ber I(2)(9), Koenig M(15), Roze E(2)(9)(10), Tranchant C(5)(6)(7), Durr A(1)(9)(10), Gaymard B(16), Anheim M(17)(18)(19)(20).
Sci Rep 2017 Nov 10;7(1):15284

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De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.

Kury S(1), van Woerden GM(2), Besnard T(3), Proietti Onori M(2), Latypova X(3), Towne MC(4), Cho MT(5), Prescott TE(6), Ploeg MA(2), Sanders S(7), Stessman HAF(8), Pujol A(9), Distel B(10), Robak LA(11), Bernstein JA(12), Denomme-Pichon AS(13), Lesca G(14), Sellars EA(15), Berg J(16), Carre W(17), Busk L(6), van Bon BWM(18), Waugh JL(19), Deardorff M(20), Hoganson GE(21), Bosanko KB(15), Johnson DS(22), Dabir T(23), Holla L(6), Sarkar A(24), Tveten K(6), de Bellescize J(25), Braathen GJ(6), Terhal PA(26), Grange DK(27), van Haeringen A(28), Lam C(29), Mirzaa G(30), Burton J(21), Bhoj EJ(31), Douglas J(32), Santani AB(33), Nesbitt AI(34), Helbig KL(35), Andrews MV(27), Begtrup A(5), Tang S(36), van Gassen KLI(26), Juusola J(5), Foss K(37), Enns GM(12), Moog U(38), Hinderhofer K(38), Paramasivam N(39), Lincoln S(32), Kusako BH(32), Lindenbaum P(40), Charpentier E(40), Nowak CB(32), Cherot E(17), Simonet T(25), Ruivenkamp CAL(28), Hahn S(29), Brownstein CA(4), Xia F(41), Schmitt S(3), Deb W(3), Bonneau D(13), Nizon M(3), Quinquis D(3), Chelly J(42), Rudolf G(43), Sanlaville D(14), Parent P(44), Gilbert-Dussardier B(45), Toutain A(46), Sutton VR(47), Thies J(48), Peart-Vissers LELM(18), Boisseau P(3), Vincent M(3), Grabrucker AM(49), Dubourg C(17); Undiagnosed Diseases Network, Tan WH(32), Verbeek NE(26), Granzow M(38), Santen GWE(28), Shendure J(50), Isidor B(3), Pasquier L(51), Redon R(40), Yang Y(41), State MW(7), Kleefstra T(18), Cogne B(3); GEM HUGO(52); Deciphering Developmental Disorders Study(53), Petrovski S(54), Retterer K(5), Eichler EE(50), Rosenfeld JA(11), Agrawal PB(55), Bezieau S(56), Odent S(51), Elgersma Y(57), Mercier S(3).
Am J Hum Genet 2017 Nov 2;101(5):768-788

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Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression.

Bonet C(1)(2), Luciani F(3)(4), Ottavi JF(1)(2), Leclerc J(1)(2), Jouenne FM(5), Boncompagni M(1)(2), Bille K(1)(2), Hofman V(2)(6), Bossis G(7), Marco de Donatis G(8), Strub T(9), Cheli Y(1)(2), Ohanna M(1)(2), Luciano F(10), Marchetti S(10), Rocchi S(1)(2), Birling MC(1)(11), Avril MF(12), Poulalhon N(13), Luc T(13), Bertolotto C(1)(2).
J Natl Cancer Inst 2017 Aug 1;109(8):djw340

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Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.

Meehan TF(1), Conte N(1), West DB(2), Jacobsen JO(3), Mason J(1), Warren J(1), Chen CK(1), Tudose I(1), Relac M(1), Matthews P(1), Karp N(4), Santos L(5), Fiegel T(5), Ring N(5), Westerberg H(5), Greenaway S(5), Sneddon D(5), Morgan H(5), Codner GF(5), Stewart ME(5), Brown J(5), Horner N(5); International Mouse Phenotyping Consortium, Haendel M(6), Washington N(7), Mungall CJ(7), Reynolds CL(8), Gallegos J(8), Gailus-Durner V(9), Sorg T(10)(11)(12)(13), Pavlovic G(10)(11)(12)(13), Bower LR(14), Moore M(15), Morse I(16), Gao X(17), Tocchini-Valentini GP(18), Obata Y(19), Cho SY(20)(21), Seong JK(20)(22), Seavitt J(8), Beaudet AL(8), Dickinson ME(8), Herault Y(10)(11)(12)(13), Wurst W(9), de Angelis MH(9), Lloyd KCK(14), Flenniken AM(23), Nutter LMJ(23), Newbigging S(23), McKerlie C(23), Justice MJ(24), Murray SA(25), Svenson KL(25), Braun RE(25), White JK(4), Bradley A(4), Flicek P(1), Wells S(5), Skarnes WC(4), Adams DJ(4), Parkinson H(1), Mallon AM(5), Brown SDM(5), Smedley D(3).
Nat Genet 2017 Aug;49(8):1231-1238

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Dry ice is a reliable substrate for the distribution of frozen mouse spermatozoa: A multi-centric study.

Raspa M(1), Guan M(2), Paoletti R(3), Montoliu L(4), Ayadi A(5), Marschall S(6); EMMA/Infrafrontier Technical Working Group, Fray M(2), Scavizzi F(7).
Theriogenology 2017 Jul 1;96():49-57

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Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE.

Birling MC(1), Schaeffer L(1), Andre P(1), Lindner L(1), Marechal D(1), Ayadi A(1), Sorg T(1), Pavlovic G(1), Herault Y(1,)(2,)(3,)(4,)(5).
Sci Rep 2017 Mar 7;7():43331

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Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors.

Haziza S(1,)(2), Mohan N(1), Loe-Mie Y(2), Lepagnol-Bestel AM(2), Massou S(1), Adam MP(1), Le XL(1), Viard J(2), Plancon C(3), Daudin R(2), Koebel P(4), Dorard E(2), Rose C(2), Hsieh FJ(5), Wu CC(6), Potier B(2), Herault Y(4), Sala C(7), Corvin A(8), Allinquant B(2), Chang HC(5), Treussart F(1), Simonneau M(1,)(2,)(9).
Nat Nanotechnol 2017 May;12(4):322-328

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Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus.

Iacono G(1), Benevento M(2)(3)(4), Dubos A(5), Herault Y(5), van Bokhoven H(2)(3)(4), Nadif Kasri N(2)(3)(4), Stunnenberg HG(6).
Sci Rep 2017 Dec 22;7(1):18073

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Modeling human disease in rodents by CRISPR/Cas9 genome editing.

Birling MC(1), Herault Y(2)(3)(4)(5)(6), Pavlovic G(2).
Mamm Genome 2017 jul 4;28(7):291-301

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Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition.

Arbogast T(1)(2)(3)(4), Iacono G(5), Chevalier C(1)(2)(3)(4), Afinowi NO(6), Houbaert X(7), van Eede MC(8), Laliberte C(8), Birling MC(9), Linda K(10), Meziane H(9), Selloum M(9), Sorg T(9), Nadif Kasri N(10), Koolen DA(10), Stunnenberg HG(5), Henkelman RM(8), Kopanitsa M(6), Humeau Y(7), De Vries BBA(10), Herault Y(1)(2)(3)(4)(9).
Plos Genet 2017 Jul 13;13(7):e1006886

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Non-invasive quantitative imaging of hepatocellular carcinoma growth in mice by micro-CT using liver-targeted iodinated nano-emulsions.

Anton N(1)(2), Parlog A(3)(4)(5)(6), Bou About G(3)(4)(5)(6), Attia MF(7)(8)(9)(10), Wattenhofer-Donze M(3)(4)(5)(6), Jacobs H(3)(4)(5)(6), Goncalves I(3)(4)(5)(6), Robinet E(11), Sorg T(3)(4)(5)(6), Vandamme TF(7)(8).
Sci Rep 2017 Oct 24;7(1):13935

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Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.

Bouabout G(1), Ayme-Dietrich E(2), Jacob H(1), Champy MF(1), Birling MC(1), Pavlovic G(1), Madeira L(2), Fertak LE(1), Petit-Demouliere B(1), Sorg T(1), Herault Y(1), Mudgett J(3), Monassier L(4).
Arch Cardiovasc Dis 2017 Nov 4

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Prevalence of sexual dimorphism in mammalian phenotypic traits.

Karp NA(1)(2), Mason J(3), Beaudet AL(4), Benjamini Y(5), Bower L(6), Braun RE(7), Brown SDM(8), Chesler EJ(7), Dickinson ME(9), Flenniken AM(10), Fuchs H(11), Angelis MH(11)(12)(13), Gao X(14), Guo S(14), Greenaway S(8), Heller R(5), Herault Y(15)(16)(17)(18)(19), Justice MJ(20), Kurbatova N(5), Lelliott CJ(21), Lloyd KCK(6), Mallon AM(8), Mank JE(22), Masuya H(23), McKerlie C(10)(24), Meehan TF(3), Mott RF(25), Murray SA(7), Parkinson H(3), Ramirez-Solis R(21), Santos L(8), Seavitt JR(4), Smedley D(26), Sorg T(15)(16)(17)(18)(19), Speak AO(21), Steel KP(21)(27), Svenson KL(7); International Mouse Phenotyping Consortium, Wakana S(23), West D(28), Wells S(8), Westerberg H(8), Yaacoby S(5), White JK(7)(21).
Nat Commun 2017 Jun 26;8():15475

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Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.

Ung DC(1,)(2), Iacono G(3), Meziane H(4), Blanchard E(1,)(5,)(6), Papon MA(1,)(2), Selten M(7), van Rhijn JR(7), Montjean R(8,)(9,)(10,)(11), Rucci J(8,)(9,)(10,)(11), Martin S(12), Fleet A(13), Birling MC(4), Marouillat S(1,)(2), Roepman R(14,)(15), Selloum M(4), Lux A(4), Thepault RA(1,)(2), Hamel P(13), Mittal K(16), Vincent JB(16), Dorseuil O(8,)(9,)(10,)(11), Stunnenberg HG(3), Billuart P(8,)(9,)(10,)(11), Nadif Kasri N(7,)(14), Herault Y(4,)(17,)(18,)(19,)(20), Laumonnier F(1,)(2,)(6).
Mol Psychiatry 2017 Apr 18

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RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents.

Elhabazi K(1), Humbert JP(2), Bertin I(3), Quillet R(4), Utard V(5), Schneider S(6), Schmitt M(7), Bourguignon JJ(8), Laboureyras E(9), Ben Boujema M(10), Simonnet G(11), Ancel C(12), Simonneaux V(13), Beltramo M(14), Bucher B(15), Sorg T(16), Meziane H(17), Schneider E(18), Petit-Demouliere B(19), Ilien B(20), Bihel F(21), Simonin F(22).
Neuropharmacology 2017 May 15;118():188-198

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Rodent models in Down syndrome research: impact and future opportunities.

Herault Y(1)(2)(3)(4)(5), Delabar JM(5)(6)(7)(8), Fisher EMC(5)(9)(10), Tybulewicz VLJ(5)(10)(11)(12), Yu E(5)(13)(14), Brault V(15)(2)(3)(4).
Dis Model Mech 2017 Oct 1;10(10):1165-1186

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Synaptic dysfunction in amygdala in intellectual disorder models.

Aincy M(1), Meziane H(2), Herault Y(3), Humeau Y(4).
Prog Neuropsychopharmacol Biol Psychiatry 2017 Jul 31

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Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

Sellier C(1), Buijsen RA(2), He F(3), Natla S(4), Jung L(5), Tropel P(5), Gaucherot A(5), Jacobs H(6), Meziane H(6), Vincent A(5), Champy MF(6), Sorg T(6), Pavlovic G(6), Wattenhofer-Donze M(6), Birling MC(6), Oulad-Abdelghani M(5), Eberling P(5), Ruffenach F(5), Joint M(5), Anheim M(7), Martinez-Cerdeno V(8), Tassone F(9), Willemsen R(2), Hukema RK(2), Viville S(10), Martinat C(11), Todd PK(12), Charlet-Berguerand N(13).
Neuron 2017 Jan 18;93(2):331-347

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