Summary

The CreERT2 Zoo mouse resource from the Institut Clinique de la Souris (ICS) is a collection of about 50 cell specific Tamoxifen inducible Cre driver lines (available as alive animals and/or frozen materials).
All lines are available to the scientific community with a materiel transfert agreement (MTA). To request a line please contact us by email at ics@igbmc.fr.

targeted cells gene name promoter reference construct type strain of origin number of backcross on C57BL/6N RT-qPCR screening done RT-qPCR extensive analysis done cre activity on reporter mice done(1) state
adipose tissue uncoupling protein 1 (mitochondrial, proton carrier) hUCP1
NCBI:7350
BAC Transgenic FVB/N 6 live embryo
adipose tissue adiponectin, C1Q and collagen domain containing hADIPOQ
NCBI:9370
BAC Transgenic FVB/N 6 live
adipose tissue Fatty acid binding protein 4 adipocyte hFABP4
NCBI:2167
BAC Transgenic FVB/N 7 live embryo
adipose tissue delta-like 1 homolog mDlk1 MGI:94900
NCBI:13386
BAC Transgenic FVB/N 11 live
beta cells insulin 1 mIns1 MGI:96572
NCBI:16333
Classical Transgenic C57BL/6J - SJL/J 9 live
cardiovascular system Myosin heavy polypeptide 6 cardiac muscle alpha mMyh6 MGI:97255
NCBI:17888
BAC Transgenic FVB/N 5 live
central nervous system Enolase 2, gamma neuronal mEno2 MGI:95394
NCBI:13807
BAC Transgenic C57BL/6J - SJL/J 4
central nervous system Nestin mNes MGI:101784
NCBI:18008
BAC Transgenic FVB/N 7 live
central nervous system calcium/calmodulin dependant protein Kinase II alpha hCAMKIIa
NCBI:815
BAC Transgenic C57BL/6J - SJL/J 5 / live
central nervous system solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 mSlc6a3 MGI:94862
NCBI:13162
BAC Transgenic C57BL/6J 8 live
central nervous system SRY-box containing gene 2 mSox2 MGI:98364
NCBI:20674
BAC Transgenic C57BL/6N pure live embryo
central nervous system plasmacytoma expressed transcript 1 mPet1 MGI:102766
NCBI:107689
BAC Transgenic C57BL/6N pure / / live
central nervous system purkinje cell protein 2 (L7) mPcp2 MGI:97508
NCBI:18545
BAC Transgenic C57BL/6J - SJL/J 10 live
central nervous system Neurofilament light polypeptide mNefl MGI:97313
NCBI:18039
BAC Transgenic FVB/N 7 live
central nervous system Calcium/calmodulin dependent protein kinase II alpha mCamkIIa MGI:88256
NCBI:12322
Classical Transgenic C57BL/6J - SJL/J 8 live
exocrine pancreatic cells Elastase 1 pancreatic mCela1 MGI:95314
NCBI:109901
BAC Transgenic C57BL/6J - SJL/J 6 live
immune system CD4 antigen mCd4 MGI:88335
NCBI:12504
BAC Transgenic FVB/N 9 live embryo
immune system platelet factor 4 mPf4 MGI:1888711
NCBI:56744
BAC Transgenic FVB/N 6 live
immune system lymphocyte protein tyrosine kinase mLck MGI:96756
NCBI:16818
BAC Transgenic FVB/N 7 live
immune system CD19 molecule hCD19
NCBI:930
BAC Transgenic C57BL/6J - SJL/J 9 live embryo
immune system Macrosialin mCd68 MGI:88342
NCBI:12514
BAC Transgenic FVB/N 9 live embryo
immune system glycoprotein 1b alpha polypeptide mGp1ba MGI:1333744
NCBI:14723
BAC Transgenic FVB/N 7 live
integumental system Keratin 14 mKrt14 MGI:96688
NCBI:16664
BAC Transgenic FVB/N 11 live
integumental system Keratin 5 hKRT5
NCBI:3852
BAC Transgenic FVB/N 6 live
integumental system Keratin 10 mKrt10 MGI:96685
NCBI:16661
BAC Transgenic FVB/N 10 live
kidney kidney androgen regulated protein mKap MGI:96653
NCBI:16483
BAC Transgenic FVB/N 8 live
macrophages Lysozyme mLyzs MGI:96897
NCBI:17105
BAC Transgenic C57BL/6J - SJL/J 5 / live
mammary gland mammary tumor virus MMTV
.
Classical Transgenic C57BL/6J - SJL/J 9 live
mucosa (glandular stomach) Ghrelin mGhrl MGI:1930008
NCBI:58991
BAC Transgenic C57BL/6J - SJL/J 11 live
myocytes troponin I, skeletal, fast 2 mTnni2 MGI:105070
NCBI:21953
BAC Transgenic C57BL/6J 9 live embryo
oocyte Zona pellucida glycoprotein mZp3 MGI:99215
NCBI:22788
BAC Transgenic C57BL/6J - SJL/J 9 live embryo
skeletal system Bone gamma carboxyglutamate protein 1 mBglap1 MGI:88156
NCBI:12096
BAC Transgenic FVB/N 9 live embryo
skeletal system Acid phosphatase 5 tartrate resistant mAcp5 MGI:87883
NCBI:11433
BAC Transgenic C57BL/6J - SJL/J 10 live embryo
skeletal system Procollagen type I alpha1 mCol1a1 MGI:88467
NCBI:12842
BAC Transgenic C57BL/6J - SJL/J 11 live
spermatocytes Phosphoglycerate kinase 2 mPgk2 MGI:97563
NCBI:18663
BAC Transgenic C57BL/6J - SJL/J 10 live
ubiquitous chicken β-actin CAG MGI:3505556
.
Other R1 ES cells pure / /
ubiquitous ROSA26 mROSA26 MGI:1861932
.
Other AK7 ES cells pure / /
ubiquitous chicken β-actin-lacZ CAG MGI:3044043
.
Classical Transgenic FVB/N pure / /
ubiquitous protein phosphatase 1A, magnesium dependent, alpha isoform mPpm1a MGI:99878
NCBI:19042
BAC Transgenic FVB/N 10 live

(1) : informations on the colorimetric floxed reporter mice are indicated in Soriano P, Nat Genet. 1999 Jan;21(1):70-1 Generalized lacZ expression with the ROSA26 Cre reporter strain