Publications

Search across publications:        168 publications found.

Antal C, Muller S, Wendling O, Hérault Y, Mark M.
Standardized, systematic, post-mortem analysis of mutant or treated adult mice.
Current protocols in Mouse Biology. 2011 1:17-53

Ayadi A,  Ferrand G , Goncalves da Cruz I, Warot X
Mouse Breeding and Colony Management
Current Protocols in Mouse Biology. 2011 1:239-264

Birling MC, Dierich A, Jacquot S, Hérault Y, Pavlovic G.
Highly-efficient, fluorescent, locus directed Cre and flpo deleter mice on a pure C57BL/6N genetic background.
Genesis. 2011 [Epub ahead of print]

Elhabazi K, Trigo J, Mollereau C, Moulédous L, Zajac JM, Bihel F, Schmitt M, Bourguignon J, Meziane H, Petit-Demoulière B, Bockel F, Maldonado R, Simonin F.
Involvement of neuropeptide FF receptors in neuroadaptative responses to acute and chronic opiate treatments.
Br J Pharmacol.. 2011 Jun 30. doi: 10.1111/j.1476-5381.2011.01563.x. [Epub ahead of print]

Gofflot F, Wendling O, Chartoire N, Birling MC, Warot X, Auwerx J
Characterization and Validation of Cre-Driver Mouse Lines
Current Protocols in Mouse Biology. 2011 1: 1-15

Herzog M, Wendling O, Guillou F, Chambon P, Mark M, Losson R, Cammas F.
TIF1β association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesis.
Dev Biol.. 2011 Feb 15;350(2):548-58. Epub 2010 Dec 14.

Lebreton A, Lakisic G, Job V, Fritsch L, Tham TN, Camejo A, Mattei PJ, Regnault B, Nahori MA, Cabanes D, Gautreau A, Ait-Si-Ali S, Dessen A, Cossart P, Bierne H.
A Bacterial Protein Targets the BAHD1 Chromatin Complex to Stimulate Type III Interferon Response.
Science. 2011 Jan 20.

Rhinn M, Schuhbaur B, Niederreither K, Dollé P.
Involvement of retinol dehydrogenase 10 in embryonic patterning and rescue of its loss of function by maternal retinaldehyde treatment.
Proc Natl Acad Sci U S A.. 2011 Oct 4;108(40):16687-92. Epub 2011 Sep 19

Suckale J, Wendling O, Masjkur J, Jäger M, Münster C, Anastassiadis K, Stewart AF, Solimena M.
PTBP1 is required for embryonic development before gastrulation.
PLoS One. 2011 Feb 17;6(2):e16992.

Blom D, Yamin TT, Champy MF, Selloum M, Bedu E, Carballo-Jane E, Gerckens L, Luell S, Meurer R, Chin J, Mudgett J, Puig O.
Altered lipoprotein metabolism in P2Y(13) knockout mice.
Biochim Biophys Acta. 2010 Sep 15.

Cammas L, Trensz F, Jellali A, Ghyselinck NB, Roux M, Dolle P.
Retinoic acid receptor alpha (RAR)-alpha is not critically required for mediating retinoic acid effects in the developing mouse retina.
Invest Ophthalmol Vis Sci. 2010 Jun;51(6):3281-90.

Champy MF, Le Voci L, Selloum M, Peterson LB, Cumiskey AM, Blom D.
Reduced body weight in male Tspan8-deficient mice.
Int J Obes (Lond). 2010 Aug 24.

Derry JM, Zhong H, Molony C, MacNeil D, Guhathakurta D, Zhang B, Mudgett J, Small K, El Fertak L, Guimond A, Selloum M, Zhao W, Champy MF, Monassier L, Vogt T, Cully D, Kasarskis A, Schadt EE.
Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.
PLoS One. 2010 Dec 14;5(12):e14319.

Deschamps K, Cromlish W, Weicker S, Lamontagne S, Huszar SL, Gauthier JY, Mudgett JS, Guimond A, Romand R, Frossard N, Percival MD, Slipetz D, Tan CM.
Genetic and Pharmacological Evaluation of Cathepsin S in a Mouse Model of Asthma.
Am J Respir Cell Mol Biol. 2010 Sep 20.

Edwards MM, Mammadova-Bach E, Alpy F, Klein A, Hicks WL, Roux M, Simon-Assmann P, Smith RS, Orend G, Wu J, Peachey NS, Naggert JK, Lefebvre O, Nishina PM.
Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation.
J Biol Chem. 2010 Mar 5;285(10):7697-711.

Facca S, Cortez C, Mendoza-Palomares C, Messadeq N, Dierich A, Johnston AP, Mainard D, Voegel JC, Caruso F, Benkirane-Jessel N.
Active multilayered capsules for in vivo bone formation.
Proc Natl Acad Sci USA. 2010 Feb 23;107(8):3406-11. Epub 2010 Feb 16.

Feige JN, Gerber A, Casals-Casas C, Yang Q, Winkler C, Bedu E, Bueno M, Gelman L, Auwerx J, Gonzalez FJ, Desvergne B.
The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms.
Environ Health Perspect. 2010 Feb;118(2):234-41.

Halter B, Gonzalez de Aguilar JL, Rene F, Petri S, Fricker B, Echaniz-Laguna A, Dupuis L, Larmet Y, Loeffler JP.
Oxidative Stress in Skeletal Muscle Stimulates Early Expression of Rad in a Mouse Model of Amyotrophic Lateral Sclerosis.
Free Radic Biol Med. 2010 Jan 12.

Liu M, Wu G, Baysarowich J, Kavana M, Addona GH, Bierilo KK, Mudgett JS, Pavlovic G, Sitlani A, Renger JJ, Hubbard BK, Fisher TS, Zerbinatti CV.
PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.
J Lipid Res. 2010 Sep;51(9):2611-8. Epub 2010 May 7.

Marty C, Lacout C, Martin A, Hasan S, Jacquot S, Birling MC, Vainchenker W, Villeval JL.
Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knock-in mice.
Blood. 2010 Aug 5;116(5):783-7. Epub 2010 May 14.

Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J; EUMODIC Consortium, de Angelis MH, Brown SD, Hancock JM, Mallon AM.
EuroPhenome: a repository for high-throughput mouse phenotyping data.
Nucleic Acids Res. 2010 Jan;38(Database issue):D577-85. Epub 2009 Nov 23.

Morsut L, Yan KP, Enzo E, Aragona M, Soligo SM, Wendling O, Mark M, Khetchoumian K, Bressan G, Chambon P, Dupont S, Losson R, Piccolo S.
Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo.
Development. 2010 Aug 1;137(15):2571-8. Epub 2010 Jun 23.

Venteo L, Bourlet T, Renois F, Douche-Aourik F, Mosnier JF, Maison GL, Pluot M, Pozzetto B, Andreoletti L.
Enterovirus-related activation of the cardiomyocyte mitochondrial apoptotic pathway in patients with acute myocarditis.
Eur Heart J. 2010 Mar;31(6):728-36. Epub 2009 Nov 19.

Argmann C, Dobrin R, Heikkinen S, Auburtin A, Pouilly L, Cock TA, Koutnikova H, Zhu J, Schadt EE, Auwerx J.
Ppargamma2 is a key driver of longevity in the mouse.
PLoS Genet.. 2009 Dec;5(12):e1000752. Epub 2009 Dec 4.

Birling MC, Gofflot F, Warot X.
Site-specific recombinases for manipulation of the mouse genome.
Methods Mol Biol. 2009 561:245-263.

Heikkinen S, Argmann C, Feige JN, Koutnikova H, Champy MF, Dali-Youcef N, Schadt EE, Laakso M, Auwerx J.
The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface.
Cell Metabolism. 2009 Jan 7;9(1):88-98.

Kolthur-Seetharam U, Teerds K, de Rooij DG, Wendling O, McBurney M, Sassone-Corsi P, Davidson I.
The histone deacetylase SIRT1 controls male fertility in mice through regulation of hypothalamic-pituitary gonadotropin signaling.
Biol Reprod. 2009 Feb;80(2):384-91. Epub 2008 Nov 5.. 2009 Feb;80(2):384-91. Epub 2008 Nov 5.

Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Haring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J.
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
PLoS Genet. 2009 Aug;5(8):e1000591. Epub 2009 Aug 7.

Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hebraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C.
A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP.
Cancer Res. 2009 Jul 1;69(13):5458-66.

Petit-Demouliere B, Masse F, Cogrel N, Hascoet M, Bourin M.
Brain structures implicated in the four-plate test in naive and experienced Swiss mice using injection of diazepam and the 5-HT2A agonist DOI.
Behav Brain Res. 2009 Dec 1;204(1):200-5. Epub 2009 Jun 10.

Wendling O, Bornert JM, Chambon P, Metzger D.
Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse.
Genesis. 2009 Jan;47(1):14-8.

Champy MF, Selloum M, Zeitler V, Caradec C, Jung B, Rousseau S, Pouilly L, Sorg T, Auwerx J.
Genetic background determines metabolic phenotypes in the mouse.
Mamm Genome. 2008 May;19(5):318-31. Epub 2008 Apr 5.

Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE.
Variations in DNA elucidate molecular networks that cause disease.
Nature. 2008 Mar 27;452(7186):429-35. Epub 2008 Mar 16.

Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, Schoonjans K, Puigserver P, O'Malley BW, Auwerx J.
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.
Proc Natl Acad Sci USA. 2008 105(44):17187-92. Epub 2008 Oct 28.

Fricker B., Muller A. and Rene F.
Evaluation Tools and Animal Models of Peripheral Neuropathies.
Neurodegenerative Disease. 2008 Jan 4

Goeldner C, Reiss D, Wichmann J, Meziane H, Kieffer BL, Ouagazzal AM.
Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in the hippocampus.
J Neurosci. 2008 Feb 27;28(9):2190-8.

Masse F, Petit-Demouliere B, Dubois I, Hascoet M, Bourin M.
Anxiolytic-like effects of DOI microinjections into the hippocampus (but not the amygdala nor the PAG) in the mice four plates test.
Behav Brain Res. 2008 Apr 9;188(2):291-7. Epub 2007 Nov 19.

Meziane H, Mandillo S, Tucci V, Holter SM, Al Banchaabouchi M, Kallnik M, Lad HV, Nolan PM, Ouagazzal AM, Coghill EL, Gale K, Golini E, Jacquot S, Krezel W, Parker A, Riet F, Schneider I, Marazziti D, Auwerx JH, Brown SD, Chambon P, Rosenthal N, Tocchini-Valentini G, Wurst W.
Reliability, Robustness and Reproducibility in mouse behavioral phenotyping: a cross-laboratory study.
Physiol Genomics. 2008 May 27.

Petit-Demouliere B, Hascoet M, Bourin M.
Factors triggering abolishment of benzodiazepines effects in the Four-Plate Test--retest in mice.
Eur Neuropsychopharmacol. 2008 Jan;18(1):41-7. Epub 2007 Jun 1.

Antal C, Teletin M, Wendling O, Dgheem M, Auwerx J, Mark M.
Tissue collection for systematic phenotyping in the mouse.
Current protocols in Mouse Biology. 2007 Oct;Chapter29:Unit29A.4

Berry A, Balard P, Coste A, Olagnier D, Lagane C, Authier H, Benoit-Vical F, Lepert JC, Seguela JP, Magnaval JF, Chambon P, Metzger D, Desvergne B, Wahli W, Auwerx J, Pipy B.
IL-13 induces expression of CD36 in human monocytes through PPARgamma activation
Eur J Immunol. 2007 37, 1642-1652.

Boucher P, Li WP, Matz RL, Takayama Y, Auwerx J, Anderson RG, Herz J.
LRP1 functions as an atheroprotective integrator of TGFbeta and PDGF signals in the vascular wall: implications for Marfan syndrome
PLoS One. 2007 2, e448.

Bourin M, Petit-Demouliere B, Dhonnchadha BN, Hascoet M.
Animal models of anxiety in mice.
Fundam Clin Pharmacol. 2007 Dec;21(6):567-74.

Coste A, Dubuquoy L, Barnouin R, Annicotte JS, Magnier B, Notti M, Corazza N, Antal MC, Metzger D, Desreumaux P, Brunner T, Auwerx J, Schoonjans K.
LRH-1 mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease
Proc Natl Acad Sci USA. 2007 104, 13098-13103.

Dali-Youcef N, Mataki C, Coste A, Messaddeq N, Giroud S, Blanc S, Koehl C, Champy MF, Chambon P, Fajas L, Metzger D, Schoonjans K, Auwerx J.
Adipose tissue specific inactivation of the retinoblastoma protein protects against diabesity due to increased energy expenditure
Proc Natl Acad Sci USA. 2007 104, 10703-10708.

Dubrac S, Stoitzner P, Pirkebner D, Elentner A, Schoonjans K, Auwerx J, Saeland S, Hengster P, Fritsch P, Romani N, Schmuth M.
Peroxisome proliferator-activated receptor alpha activation inhibits Langerhans cell function
J Immunol. 2007 178, 4362-4372.

Fergani A, Oudart H, Gonzalez De Aguilar JL, Fricker B, Rene F, Hocquette JF, Meininger V, Dupuis L, Loeffler JP.
Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis.
Journal of Lipid Research. 2007 Apr 16.

Gofflot F, Chartoire N, Vasseur L, Heikkinen S, Dembele D, Le Merrer J, Auwerx J.
Systematic gene expression mapping clusters nuclear receptors on the basis of their function in the brain
Cell. 2007 131, 405-418.

Grarup N, Andersen MK, Andreasen CH, Albrechtsen A, Borch-Johnsen K, Jorgensen T, Auwerx J, Schmitz O, Hansen T and Pedersen O.
Studies of the relationship between the common DIO2 Thr92Ala polymorphism and type 2 diabetes, obesity and insulin resistance in 7,342 Danish white subjects: indication of gene-gene interaction with the ADRB2 Gly16Arg variant on levels of fasting glycaemia in the general population
J Clin Endocrinol Metab. 2007 92, 636-366.

Guimond A, Teletin M, Garo E, D'Sa A, Selloum M, Champy MF, Vonesch JL, Monassier L.
Quantitative ultrasonic tissue characterization as a new tool for continuous monitoring of chronic liver remodelling in mice
Liver International. 2007 27, 854-864.

Houten SM, Volle DH, Cummins CL, Mangelsdorf DJ, Auwerx J.
In vivo imaging of FXR activity reveals the ileum as the primary bile acid signaling tissue
Mol Endocrinol. 2007 21, 1312-1323.

Mark M, Teletin M, Antal C, Wendling O, Auwerx J, Heikkinen S, Khetchoumian K, Argmann CA, Dgheem M.
Histopathology in mouse metabolic investigations.
Current protocols in Mouse Biology. 2007 Apr;Chapter29;Unit29B.4

Masson R, Sorg T and Warot X
Genomique fonctionnelle de la souris : la dynamique europeenne
Med & Sci October 2007. 2007 Volume 23, n 10.

Petit-Demouliere B, Bourin M.
Temporal parameters of one-trial tolerance to benzodiazepines in four-plate test-retest.
Behav Brain Res. 2007 Nov 2;183(2):222-5. Epub 2007 Jun 13.

Volle DH, Duggavathi R, Magnier BC, Houten SM, Cummins CL, Lobaccaro JM, Verhoeven G, Schoonjans K, Auwerx J.
The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice
Genes & Dev. 2007 21, 303-315.

Welter M, Vallone D, Samad TA, Meziane H, Usiello A, Borrelli E.
Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaine.
Proc Natl Acad Sci USA. 2007 104: 6840-6845.

Andrieu D, Meziane H, Marly F, Angelats C, Fernandez PA, Muscatelli F.
Sensory defects in necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death
BMC Develop Biol. 2006 6, 56.

Argmann CA, Auwerx J.
Collection of blood and plasma from the mouse
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29A.3.1-29A.3.4.

Argmann CA, Auwerx J.
Minimizing variation due to genotype and environment
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29A.2.1-29A.2.3.

Argmann CA, Champy MF, Auwerx J.
Evaluation of energy homeostasis
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29B.1.1-29B.1.17.

Argmann CA, Dierich A, Auwerx J.
Uses of forward and reverse genetics in mice to study gene function
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29A1.1-29A1.8.

Argmann CA, Houten SM, Champy MF, Auwerx J.
Lipid and bile acid analysis
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29B.2.1-29B.2.24.

Calleja C, Messaddeq N, Chapellier B, Yang H, Krezel W, Li M, Metzger D, Mascrez B, Ohta K, Kagechika H, Endo Y, Mark M, Ghyselinck NB, Chambon P.
Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes
Genes & Dev. 2006 20, 1525-1538.

Champy MF, Argmann CA, Chambon P, Auwerx J.
Exploration of metabolic and endocrine function in the mouse
Standards of Mouse Model Phenotyping (Eds M. Hrabe de Angelis, P. Chambon, S. Brown). 2006 109-134.

Chotteau-Lelievre A, Dolle P, Gofflot F.
Expression analysis of murine genes using in situ hybridization with radioactive and non-radioactively labeled probes.
Methods in Molecular Biology : In Situ Hybridization Protocols, 3rd Edition 2005.. 2006

Cobb J, Dierich A, Huss-Garcia Y, Duboule D.
A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development
Proc Natl Acad Sci USA. 2006 103, 4511-4515.

Contet C, Gaveriaux-Ruff C, Matifas A, Caradec C, Champy MF, Kieffer BL.
Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice
Neuropsychopharmacology. 2006 31, 1733-1744.

Coste A, Antal MC, Chan S, Kastner P, Mark M, O'Malley BW, Auwerx J.
Absence of the steroid receptor coactivator 3 (SRC-3) induces B cell lymphoma
EMBO J. 2006 25, 2453-2464.

Dierich A, Le Guen E, Messaddeq N, Schaaf P, Voegel JC, Jessel N.
Bone formation mediated by growth factors embedded in a polyelectrolyte multilayer film
Advanced Materials. 2006

Duval D, Trouillas M, Thibault C, Dembele D, Diemunsch F, Reinhardt B, Mertz AL, Dierich A, Boeuf H.
Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cells
Cell Death Differ. 2006 13, 564-575.

Ghyselinck NB, Vernet N, Dennefeld C, Giese N, Nau H, Chambon P, Viville S, Mark M.
Retinoids and spermatogenesis: lessons from mutant mice lacking the plasma retinol binding protein
Dev Dyn. 2006 235, 1608-1622.

Goetz C, Choquet P, Monassier L, Breton E, El Fertak L, Constantinesco A.
Hepatobilary morphology and function in normal mice using micro-CT and planar pinhole scintigraphy
ITBM-RBM. 2006 27, 194-202.

Heikkinen S, Argmann CA, Champy MF, Auwerx J.
Evaluation of glucose homeostasis
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29B.3.1-29B3.22.

Houten SM, Watanabe M, Auwerx J.
Endocrine functions of bile acids
EMBO J. 2006 25, 1419-1425.

Imayoshi I, Ohtsuka T, Metzger D, Chambon P, Kageyama R.
Temporal regulation of Cre recombinase activity in neural stem cells
Genesis. 2006 44, 233-238.

Indra AK, Castaneda E, Antal MC, Jiang M, Messaddeq N, Meng X, Loehr CV, Gariglio P, Kato S, Wahli W, Desvergne B, Metzger D, Chambon P.
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
J Investigative Dermatol. 2006 127, 1250-1260.

Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J.
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Cell. 2006 127, 1109-1122.

Lamprianou S, Vacaresse N, Suzuki Y, Meziane H, Buxbaum JD, Schlessinger J, Harroch S.
Receptor protein tyrosine phosphatase gamma is a marker for pyramidal cells and sensory neurons in the nervous system and is not ncessary for normal development
Mol Cell Biol. 2006 26, 5106-5119.

Li M, Hener P, Zhang Z, Kato S, Metzger D, Chambon P.
Topical vitamin D3 and low calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis
Proc Natl Acad Sci USA. 2006 103, 11736-11741.

Li XG, Okada T, Kodera M, Nara Y, Takino N, Muramatsu C, Ikeguchi K, Urano F, Ichinose H, Metzger D, Chambon P, Nakano I, Ozawa K, Muramatsu S.
Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease.
Molecular Therapy. 2006 13, 160-166.

Loichot C, Jesel L, Tesse A, Tabernero A, Schoonjans K, Roul G, Carpusca I, Auwerx J, Andriantsitohaina R.
Deletion of peroxisome proliferator-activated receptor-alpha induces an alteration of cardiac functions.
Am J Pathol Heart Circ Physiol. 2006 291, H161-166.

Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW
Oncogenic stetroid receptor coactivator-3 is a key regulator of the white adipogenic program
Proc Natl Acad Sci USA. 2006 103, 17868-17873.

Mark M, Ghyselinck NB, Chambon P.
Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis
Annu Rev Pharmacol Toxicol. 2006 46, 451-480.

Mark M, Teletin M, Antal C, Wendling O, Auwerx J, Heikkinen S, Khetchoumian K, Argmann C, Dgheem M.
Histopathology in mouse metabolic investigations
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29B.4.1-29B4.32.

Matsumoto S, Banine F, Struve J, Xing R, Adams C, Liu Y, Metzger D, Chambon P, Rao MS, Sherman LS.
Brg1 is required for murine neural stem cell maintenance and gliogenesis
Developmental Biology. 2006 289, 372-383.

Meziane H, Ouagazzal AM, Aubert L, Wietrzych M, Krezel W.
Estrous cycle effects on behavior of C57BL/6J and BALB/cByJ female mice: implications for phenotyping strategies
Genes, Brain & Behavior. 2006 6, 192-200.

Monassier L, Combe R, El Fertak L.
Mice models of hypertension
Drug Discovery. 2006

Monassier L, Constantinesco A.
Cardiovascular disorders: insights into in vivo cardiovascular phenotyping
Standards of Mouse Model Phenotyping (Eds M. Hrabe de Angelis, P. Chambon, S. Brown). 2006 177-199.

Moore DD
Mouse Phenotyping : INTRODUCTION
Current Protocols in Molecular Biology (Ed. D.D. Moore). 2006 29.0.1.

Nenci A, Huth M, Funteh A, Schmidt-Supprian M, Bloch W, Metzger D, Chambon P, Rajewsky K, Krieg T, Haase I, Pasparakis M.
Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling
Human Mol Gen. 2006 15. 531-542.

Oskarsson T, Essers MA, Dubois N, Offner S, Dubey C, Roger C, Metzger D, Chambon P, Hummler E, Beard P, Trumpp A.
Skin epidermis lacking the c-myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene
Genes & Dev. 2006 20, 2024-2029.

Peltola P, Pihlajamaki J, Koutnikova H, Ruotsalainen E, Salmenniemi U, Vauhkonen I, Kainulainen S, Gylling H, Miettinen TA, Auwerx J, Laakso M.
Visceral obesity is associated with high levels of serum squalene
Obesity. 2006 14, 1155-1163.

Rodriguez A, Duran A, Selloum M, Champy MF, Diez-Guerra FJ, Flores JM, Serrano M, Auwerx J, Diaz-Meco MT, Moscat J.
Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.
Cell Metabolism. 2006 3, 211-222.

Romand R, Dolle P, Hashino E.
Retinoids signaling in inner ear development
J Neurobiology. 2006 66, 687-704.

Romand R, Kondo T, Fraulob V, Petkovich M, Dolle P, Hashino E.
Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear
J Comp Neurology. 2006 496, 643-654.

Scherrer G, Tryoen-Toth P, Filliol D, Matifas A, Laustriat D, Cao YQ, Basbaum AI, Dierich A, Vonesh JL, Gaveriaux-Ruff C, Kieffer BL.
Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo
Proc Natl Acad Sci USA. 2006 103, 9691-9696.

Schuler M, Ali F, Chambon C, Duteil D, Bornert JM, Tardivel A, Desvergne B, Wahli W, Chambon P, Metzger D.
PGC1alpha expression is controlled in skeletal muscles by PPARbeta whose ablation results in fiber type switching, obesity and type 2 diabetes
Cell Metabolism. 2006 4, 407-414.

Stratis A, Pasparakis M, Markur D, Knaup R, Pofahl R, Metzger D, Chambon P, Krieg T, Haase I.
Localized inflammatory skin disease following inducible ablation of I kappa B kinase 2 in epidermal keratinocytes of the mouse
J Investigative Dermatol. 2006 126, 614-620.

Vermot J, Garnier JM, Dierich A, Niederreither K, Harvey RP, Chambon P, Dolle P.
Conditional (loxP-flanked allelefor the gene encoding the retinoic acid-synthesizing enzyme retinaldehyde dehydrogenase 2 (RALDH2)
Genesis. 2006 44, 155-158.

Vernet N, Dennefeld C, Rochette-Egly C, Oulad-Abdelghani M, Chambon P, Ghyselinck NB, Mark M.
Retinoic acid metabolism and signaling pathways in the adult and developing mouse testis
Endocrinology. 2006 147, 96-110.

Zoll J, Monassier L, Garnier A, N'Guessan B, Mettauer B, Veksler V, Piquard F, Ventura-Clapier R, Geny B.
ACE inhibition prevents myocardial infarction-induced skeketal muscle mitochondrial dysfunction
J Appl Physiol. 2006 101, 385-391.

Abdeljalil J, Hamid M, Abdel-Mouttalib O, Stephane R, Raymond R, Johan A, Jose S, Pierre C, Serge P.
The optomotor response: a robust first-line visual screening method for mice.
Vision Res. 2005 45, 1439-1446.

Argmann CA, Chambon P, Auwerx J.
Mouse phenogenomics: the fast track to systems metabolism
Cell Metabolism. 2005 2, 349-360.

Argmann CA, Cock TA, Auwerx J.
Peroxisome proliferators-activated receptor gamma: the more the merrier?
Eur J Clin Invest. 2005 35, 82-92.

Brown SD, Chambon P, de Angelis MH; Eumorphia Consortium.
EMPReSS: Standardized phenotype screens for functional annotation of the mouse genome
Nature Genetics. 2005 17, 1155.

Constantinesco A, Choquet P, Monassier L, Israel-Jost V, Mertz L.
Assessment of left ventricular perfusion, volumes,and motion in mice using pinhole gated SPECT
J Nuclear Medicine. 2005 46, 1005-1011.

Dharancy S, Malapel M, Perlemuter G, Roskams T, Cheng Y, Dubuquoy L, Podevin P, Conti F, Canva V, Philippe D, Gambiez L, Mathurin P, Paris JC, Schoonjans K, Calmus Y, Pol S, Auwerx J, Desreumaux P.
Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection.
Gastroenterology. 2005 128, 334-342.

Indra AK, Mohan WS 2nd, Frontini M, Scheer E, Messaddeq N, Metzger D, Tora L.
TAF10 is required for the stablishment of skin barrier function in foetal, but not adult mouse epidermis
Developmental Biology. 2005 285, 28-37.

Martin M, Gallego-Llamas J, Ribes V, Kedinger M, Niederreither K, Chambon P, Dolle P, Gradwohl G.
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice
Developmental Biology. 2005 284, 399-411.

Matt N, Dupe V, Garnier JM, Dennefeld C, Chambon P, Mark M, Ghyselinck NB.
Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells
Development. 2005 132, 4789-4800.

Matt N, Schmidt CK, Dupe V, Dennefeld C, Nau H, Chambon P, Mark M, Ghyselinck NB.
Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development
Dev Dyn. 2005 233, 167-176.

Metzger D, Imai T, Jiang M, Takukawa R, Desvergne B, Wahli W, Chambon P.
Functional role of RXRs and PPARgamma in mature adipocytes
Prostaglandins, Leukotrienes & Essential Fatty Acids. 2005 73, 51-58.

Metzger D, Li M, Indra AK, Schuler M, Chambon P.
Conditional knockouts: Cre-Lox systems.
Cell Biology: A Laboratory Handbook . 2005 3, 53

Schnutgen F, De-Zolt S, Van Sloun P, Hollatz M, Floss T, Hansen J, Altschmied J, Seisenberger C, Ghyselinck NB, Ruiz P, Chambon P, Wurst W, von Melchner H.
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome
Proc Natl Acad Sci USA. 2005 102, 7221-7226.

Schoonjans K, Dubuquoy L, Mebis J, Fayard E, Wendling O, Haby C, Geboes K, Auwerx J.
Liver Receptor Homolog 1 contributes to colon tumor formation.
Proc Natl Acad Sci USA. 2005 102, 2058-2062.

Schuler M, Ali F, Metzger E, Chambon P, Metzger D.
Temporally-controlled somatic mutagenesis in skeletal muscles of the mouse
Genesis. 2005 41, 165-170.

Wietrzych M, Meziane H, Sutter A, Ghyselinck N, Chapman PF, Chambon P, Krezel W.
Working memory deficits in retinoid X receptor gamma-deficient mice
Learning & Memory. 2005 12, 318-326.

Annicotte JS, Schoonjans K, Auwerx J.
Expression of the liver X receptor alpha and beta in embryonic and adult mice.
Anat Rec. 2004 277A, 312-316.

Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, de Angelis MH, Jackson I, Kioussis D, Kollias G, Lathrop M, Lendahl U, Malumbres M, von Melchner H, Muller W, Partanen J, Ricciardi-Castagnoli P, Rigby P, Rosen B, Rosenthal N, Skarnes B, Stewart AF, Thornton J, Tocchini-Valentini G, Wagner E, Wahli W, Wurst W.
The European dimension for the mouse genome mutagenesis program
Nature Genetics. 2004 36, 925-927 ; erratum in Nat. Genet. 2004, 36, 1238.

Back J, Dierich A, Bronn C, Kastner P, Chan S.
PU.1 determines the self renewal capacity of erythroid progenitor cells
Blood. 2004 103, 3615-3623.

Botrugno OA, Fayard E, Annicotte JS, Haby C, Brennan T, Wendling O, Tanaka T, Kodama T, Thomas W, Auwerx J, Schoonjans K.
Synergy between LRH-1 and beta-catenin induces cyclin-mediated cell proliferation.
Mol Cell. 2004 15, 499-509.

Bousquet P, Greney H, Bruban V, Schann S, Ehrhardt JD, Monassier L, Feldman J.
I(1) imidazoline receptors involved in cardiovascular regulation: where are we and where are we going?
Ann N Y Acad Sci. 2004 1009, 228-233.

Champy MF, Selloum M, Piard L, Zeitler V, Caradec C, Chambon P, Auwerx J.
Mouse functional genomics requires standardization of mouse handling and housing conditions.
Mamm Genome. 2004 15, 768-783.

Cock TA, Houten SM, Auwerx J.
Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm.
EMBO rep. 2004 5, 142-147.

Dierich A, Kieffer BL.
Knockout Mouse Models in Pain Research.
Methods Mol. Med. - Pain Research: Methods & Protocols (Ed. Z. Luo, Humana Press Inc., Totowa NJ). 2004 99, 269-300.

el Marjou F, Janssen KP, Chang BH, Li M, Hindie V, Chan L, Louvard D, Chambon P, Metzger D, Robine S.
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
Genesis. 2004 39, 186-193.

Fajas L, Annicotte JS, Miard S, Sarruf D, Watanabe M, Auwerx J.
Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/-) mice.
J Clin Invest. 2004 113, 1288-1295.

Fayard E, Auwerx J, Schoonjans K.
LRH-1 : an orphan nuclear receptor involved in development, metabolism, and steroidogenesis.
Trends in Cell Biology. 2004 14, 250-260.

Helmlinger D, Abou-Sleymane G, Yvert G, Rousseau S, Weber C, Trottier Y, Mandel JL, Devys D.
Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model
J Neurosci. 2004 24, 1881-1887.

Imai T, Takakuwa R, Marchand S, Dentz E, Bornert JM, Messaddeq N, Wendling O, Mark M, Desvergne B, Wahli W, Chambon P, Metzger D.
Peroxisome proliferators-activated receptor is required in mature white and brown adipocytes for their survival in the mouse.
Proc Natl Acad Sci USA. 2004 101, 4543 - 4547.

Jaffre F, Callebert J, Sarre A, Etienne N, Nebigil CG, Launay JM, Maroteaux L, Monassier L.
Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: role of IL-6, IL-1beta and TNF-alpha cytokine production by ventricular fibroblast
Circulation. 2004 110? 969-974.

Mark M, Ghyselinck NB, Chambon P.
Retinoic acid signalling in the development of branchial arches
Curr Opin Genet Dev. 2004 14, 591-598.

Mark M, Yoshida-Komiya H, Gehin M, Liao L, Tsai MJ, O'Malley BW, Chambon P, Xu J.
Partially redundant functions of SRC-1 and TIF2 in post natal survival and male reproduction
Proc Natl Acad Sci USA. 2004 101, 4453-4458.

Mascrez B, Ghyselinck NB, Watanabe M, Annicotte JS, Chambon P, Auwerx J, Mark M.
Ligand-dependent contribution of RXRb to cholesterol homeostasis in Sertoli cells.
EMBO rep. 2004 5, 285-290.

Metzger D, Chambon P.
Cre-mediated conditional gene targeting to understand liver functions.
Drug Discovery Today. 2004 1, 229-234.

Metzger D, Li M, Chambon P.
Targeted somatic mutagenesis in the mouse epidermis.
Epidermal Cells : Methods and Protocols. 2005, The Humana Press Inc. Totowa, New Jersey, USA. . 2004 289, 329-340.

Monassier L, Theodoropoulos C, Sandler R, Constantinesco A.
Current mouse models for studying cardiac dysfunctions: technical and imaging aspects.
Drug Discovery Today. 2004 1, 235-241.

Mori M, Metzger D, Picaud S, Hhindelang C, Simonutti M, Sahel J, Chambon P, Mark M
Retinal dystrophy resulting from ablation of retinoid X receptor alpha (RXRalpha) in mouse retinal pigment epithelium
Am J Pathol. 2004 164, 701-710.

Mori M, Metzger D, Picaud S, Hindelang C, Simonutti M, Sahel J, Chambon P, Mark M.
Retinal dystrophy resulting from ablation of retinoid X receptora (RXRa) in mouse retinal pigment epithelium.
Am J Pathol. 2004 164, 701 - 710.

Schuler M, Dierich A, Chambon P, Metzger D.
Efficient temporally-controlled somatic mutagenesis in hepatocytes of the mouse.
Genesis. 2004 39, 167-172.

Seznec H, Simon D, Monassier L, Criqui-Filipe P, Gansmuller A, Rustin P, Koenig M, Puccio H.
Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxia
Human Mol Gen. 2004 13, 1017-1024.

Thomas L, Bellmont S, Christen MO, La Roche B, Monassier L.
Cardiovascular and survival effects of sympatho-inhibitors in adriamycin-induced cardiomyopathy in rats.
Fundam Clin Pharmacol. 2004 18, 649-655.

Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, Fumagalli S, Allegrini PR, Kozma SC, Auwerx J, Thomas G.
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.
Nature. 2004 431, 200-205.

Watanabe M, Houten SM, Wang L, Moschetta A, Mangelsdorf DJ, Heyman RA, Moore DD, Auwerx J.
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.
J Clin Invest. 2004 113, 1408-1418.

Yan KP, Dollé P, Mark M, Lerouge T, Wendling O, Chambon P, Losson R.
Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1 gamma gene.
Gene.. 2004 Jun 9;334:3-13.

Annicotte JS, Fayard E, Swift GH, Selander L, Edlund H, Tanaka T, Kodama T, Schoonjans K, Auwerx J.
Pancreatic-duodenal homeobox-1 (PDX-1) regulates the expression of the liver receptor homolog 1 (LRH-1) during pancreas development.
Mol Cell Biol. 2003 23, 6713-6724.

Arnaud-Dabernat S, Bourbon PM, Dierich A, Le Meur M, Daniel JY.
Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 gene
J Bioenerg & Biomembr. 2003 25, 19-30.

Auwerx J, Drouin J, Laudet V.
Recepteurs a la Provencale. EMBO workshop on the biology of nuclear receptors.
EMBO rep. 2003 4, 1122-1126.

Cock TA, Auwerx J.
Leptin: cutting the fat of the bone.
The Lancet. 2003 362, 1572-1574.

Delarasse C, Daubas P, Mars LT, Vizler C, Litzenburger T, Iglesias A, Bauer J, Della Gaspera B, Schubart A, Decker L, Dimitri D, Roussel G, Dierich A, Amor S, Dautigny A, Liblau R, Pham-Dinh D.
Myelin/oligodendrocyte glycoprotein-deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice
J Clin Invest. 2003 112, 544-553.

Dupe V, Matt N, Garnier JM, Chambon P, Mark M, Ghyselinck NB.
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment
Proc Natl Acad Sci USA. 2003 100, 14036-14041.

Koutnikova H, Cock TA, Watanabe M, Houten SM, Champy MF, Dierich A, Auwerx J.
Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARgamma hypomorphic mice
Proc Natl Acad Sci USA. 2003 100, 14457-14462.

Menissier de Murcia J, Ricoul M, Tartier L, Niedergang C, Huber A, Dantzer F, Schreiber V, Ame JC, Dierich A, LeMeur M, Sabatier L, Chambon P, de Murcia G.
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse
EMBO J. 2003 22, 2255-2263.

Mohan WS Jr, Scheer E, Wendling O, Metzger D, Tora L.
TAF10 (TAF(II)30) is necessary for TFIID stability and early embryogenesis in mice.
Mol Cell Biol.. 2003 Jun;23(12):4307-18.

Nebigil CG, Jaffre F, Messaddeq N, Hickel P, Monassier L, Launay JM, Maroteaux L.
Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy
Circulation. 2003 107, 3223-3229.

Rayasam GV, Wendling O, Angrand PO, Mark M, Niederreither K, Song L, Lerouge T, Hager GL, Chambon P, Losson R.
NSD1 is essential for early post-implantation development and has a catalytically active SET domain.
EMBO J.. 2003 Jun 16;22(12):3153-63.

Schnütgen F, Doerflinger N, Calléja C, Wendling O, Chambon P, Ghyselinck NB.
A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse.
Nat Biotechnol.. 2003 May;21(5):562-5. Epub 2003 Mar 31.

Bruban V, Estato V, Schann S, Ehrhardt JD, Monassier L, Renard P, Scalbert E, Feldman J, Bousquet P.
Evidence for synergy between alpha(2)-adrenergic and nonadrenergic mechanisms in central blood pressure regulation
Circulation. 2002 105, 1116-11121.

Chapellier B, Mark M, Bastien J, Dierich A, LeMeur M, Chambon P, Ghyselinck NB.
A conditional floxed (loxP-flanked) alleme for the retinoic acid receptor beta (RARbeta) gene
Genesis. 2002 32, 91-94.

Chapellier B, Mark M, Garnier JM, Dierich A, Chambon P, Ghyselinck NB.
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RARgamma) gene
Genesis. 2002 32, 95-98.

Fajas L, Egler V, Reiter R, Hansen J, Kristiansen K, Debril MB, Miard S, Auwerx J.
The retinoblastoma-histone deacetylase 3 complex inhibits the peroxisome proliferator-activated receptor gamma and adipocyte differentiation.
Developmental Cell. 2002 3,903-910.

Gehin M, Mark M, Dennefeld C, Dierich A, Gronemeyer H, Chambon P.
The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP
Mol Cell Biol. 2002 16, 5923-5937.

Monassier L, Bousquet P.
Sigma receptors: from discovery to hightlights of their implications in the cardiovascular system
Fundam Clin Pharmacol. 2002 16, 1-8.

Pasqualetti M, Ren SY, Poulet M, LeMeur M, Dierich A, Rijli FM.
A Hoxa2 knockin allele that expresses EGFP upon conditional Cre-mediated recombinaison.
Genesis. 2002 32, 109-111.

Picard F, Gehin M, Annicotte J, Rocchi S, Champy MF, O'Malley BW, Chambon P, Auwerx J.
SRC-1 and TIF2 control energy balance between white and brown adipose tissues.
Cell. 2002 111, 931-941.

Picard F, Wanatabe M, Schoonjans K, Lydon J, O'Malley BW, Auwerx J.
Progesterone receptor knock-out mice have an improved glucose homeostasis secondary to ?-cell proliferation.
Proc Natl Acad Sci USA. 2002 99, 15644-15648.

Ren SY, Pasqualetti M, Dierich A, Le Meur M, Rijli FM.
A Hoxa2 mutant conditional allele generated by Flp- and Cre-mediated recombinaison
Genesis. 2002 32, 105-108.

Schoonjans K, Annicotte JS, Huby T, Botrugno OA, Fayard E, Ueda Y, Chapman J, Auwerx J.
Liver receptor homolog I controls the expression of the scavenger receptor class B type I.
EMBO rep. 2002 3, 1181-87.