Institut Clinique de la Souris
|
News
Monterotondo Cryo Course 2010
The poster and application form of the 2010 Monterotondo Course on
Cryopreservation of Mouse Germplasm are now on-line
(2010 section).
The Course will be held on October 25 to 29, 2010. Deadline for
application is Sept. 25, 2010.
Focus
Transnational Access (TA) activity of the EMMAservice project: Free of charge access to EMMA mouse mutant resources
read more ...
|
The mouse occupies a pivotal position amongst model organisms used in
bio-medical research. The mouse genetics toolkit, including the generation
of targeted spatio-temporally-controlled somatic mutations, allows us to
introduce a range of informative mutations in almost any gene. Its
potential, when coupled to appropriate phenotyping platforms, to dissect
the role of each gene in (patho)physiological and biochemical pathways,
making it an unparalleled vehicle for functional genomics studies.
Due to its small size, fast generation time, and the strong developmental,
physiological and biochemical similarities between mouse and man, the
mouse has now become also a valuable model for pharmacology and toxicology.
In fact, the same phenotyping platforms can also be used to test the
efficacy and determine the side-effects of drug treatments.
One of the main missions of the ICS is to provide a comprehensive array
of services for the "mouse" scientific community (see under Services).
These activities span from the generation of new mouse models to
phenotyping platforms. In addition, the ICS has an in house research
and developmental program (see under Research).
The ICS is organized as an integrated technology laboratory with 5
highly interactive service platforms, some of which are jointly operated
with the Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC).
The ICS is housed in a facility of ± 6000 m2 with a capacity
to house up to 70,000 mice and employs 93 persons devoted to the
generation, care, and analysis of mouse models.
Each platform is managed by a specialist in the respective field,
who is assisted by outside consultants from the IGBMC and the Strasbourg Genopole.
Importantly, all phenotyping activities are carefully validated in
several different mice strains and the procedures are standardized in
close collaboration with the
EU-funded mouse phenotyping projects.
I.C.S. : 1, rue Laurent Fries - BP 10142 - 67404 ILLKIRCH CEDEX
Director : Dr. Yann Hérault