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2018A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.Dubos A(1)(2)(3)(4), Meziane H(4), Iacono G(5), Curie A(6), Riet F(4), Martin C(7), Loaec N(8), Birling MC(4), Selloum M(4), Normand E(7)(9), Pavlovic G(4), Sorg T(4), Stunnenberg HG(5), Chelly J(1)(2)(3)(10), Humeau Y(7), Friocourt G(8), Herault Y(1)(2)(3)(4). |
Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A.Nguyen TL(1)(2)(3)(4)(5), Duchon A(1)(2)(3)(4), Manousopoulou A(6), Loaec N(5), Villiers B(5), Pani G(1)(2)(3)(4), Karatas M(7)(8), Mechling AE(8), Harsan LA(7)(8), Limanton E(9), Bazureau JP(9), Carreaux F(9), Garbis SD(10), Meijer L(11), Herault Y(12)(2)(3)(4). |
Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome.Iacono G(1), Dubos A(2)(3)(4)(5), Meziane H(2), Benevento M(6)(7)(8), Habibi E(1), Mandoli A(1), Riet F(2), Selloum M(2), Feil R(9)(10), Zhou H(1)(7), Kleefstra T(7)(8), Kasri NN(6)(7)(8), van Bokhoven H(6)(7)(8), Herault Y(2)(3)(4)(5), Stunnenberg HG(1). |
Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.Bouabout G(1), Ayme-Dietrich E(2), Jacob H(1), Champy MF(1), Birling MC(1), Pavlovic G(1), Madeira L(2), Fertak LE(1), Petit-Demouliere B(1), Sorg T(1), Herault Y(1), Mudgett J(3), Monassier L(4). |
Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.Ung DC(1)(2), Iacono G(3), Meziane H(4), Blanchard E(1)(5)(6), Papon MA(1)(2), Selten M(7), van Rhijn JR(7), Montjean R(8)(9)(10)(11), Rucci J(8)(9)(10)(11), Martin S(12), Fleet A(13), Birling MC(4), Marouillat S(1)(2), Roepman R(14)(15), Selloum M(4), Lux A(4), Thepault RA(1)(2), Hamel P(13), Mittal K(16), Vincent JB(16), Dorseuil O(8)(9)(10)(11), Stunnenberg HG(3), Billuart P(8)(9)(10)(11), Nadif Kasri N(7)(14), Herault Y(4)(17)(18)(19)(20), Laumonnier F(1)(2)(6). |
Synaptic dysfunction in amygdala in intellectual disorder models.Aincy M(1), Meziane H(2), Herault Y(3), Humeau Y(4). |
Translating molecular advances in Down syndrome and Fragile X syndrome into therapies.Faundez V(1), De Toma I(2), Bardoni B(3), Bartesaghi R(4), Nizetic D(5), de la Torre R(6), Cohen Kadosh R(7), Herault Y(8), Dierssen M(9), Potier MC(10); Down Syndrome and Other Genetic Developmental Disorders ECNP Network. |
2017A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse.Daubeuf F(1)(2), Becker J(3), Aguilar-Pimentel JA(4), Ebel C(5), Hrabe de Angelis M(4), Herault Y(3)(5)(6)(7)(8), Frossard N(1)(2). |
A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.Bowl MR(1), Simon MM(1), Ingham NJ(2)(3), Greenaway S(1), Santos L(1), Cater H(1), Taylor S(1), Mason J(4), Kurbatova N(4), Pearson S(3), Bower LR(5), Clary DA(5), Meziane H(6), Reilly P(6), Minowa O(7), Kelsey L(8)(9)(10); International Mouse Phenotyping Consortium, Tocchini-Valentini GP(11), Gao X(12), Bradley A(3), Skarnes WC(3), Moore M(13), Beaudet AL(14), Justice MJ(8)(9)(10)(14), Seavitt J(14), Dickinson ME(15), Wurst W(16), de Angelis MH(17), Herault Y(6)(18)(19)(20), Wakana S(7), Nutter LMJ(8)(9)(10), Flenniken AM(8)(9)(10), McKerlie C(8)(9)(10), Murray SA(21), Svenson KL(21), Braun RE(21), West DB(22), Lloyd KCK(5), Adams DJ(3), White J(3), Karp N(3), Flicek P(4), Smedley D(23), Meehan TF(4), Parkinson HE(4), Teboul LM(1), Wells S(1), Steel KP(2)(3), Mallon AM(1), Brown SDM(24). |
Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies.Wendling O(1), Champy MF(1), Jaubert S(2), Pavlovic G(1), Dubos A(1)(3)(4)(5)(6), Lindner L(1), Jacobs H(1), Mark M(1)(3)(4)(5)(6), Combe R(1), Da Cruz IG(1), Luche H(6), Mudgett JS(7), Rosahl T(7), Sorg T(1), Malissen M(2), Reilly PT(1), Herault Y(8)(9)(10)(11)(12). |
Comparing ataxias with oculomotor apraxia: a multimodal study of AOA1, AOA2 and AT focusing on video-oculography and alpha-fetoprotein.Mariani LL(1)(2), Rivaud-Pechoux S(3), Charles P(1), Ewenczyk C(1), Meneret A(2)(3), Monga BB(4), Fleury MC(5)(6)(7), Hainque E(8)(9)(10), Maisonobe T(11), Degos B(2), Echaniz-Laguna A(5)(12), Renaud M(5)(6)(7), Wirth T(5), Grabli D(2)(9), Brice A(1)(9)(10), Vidailhet M(2)(9)(10), Stoppa-Lyonnet D(13)(14), Dubois-d'Enghien C(13), Le Ber I(2)(9), Koenig M(15), Roze E(2)(9)(10), Tranchant C(5)(6)(7), Durr A(1)(9)(10), Gaymard B(16), Anheim M(17)(18)(19)(20). |
Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression.Bonet C(1)(2), Luciani F(3)(4), Ottavi JF(1)(2), Leclerc J(1)(2), Jouenne FM(5), Boncompagni M(1)(2), Bille K(1)(2), Hofman V(2)(6), Bossis G(7), Marco de Donatis G(8), Strub T(9), Cheli Y(1)(2), Ohanna M(1)(2), Luciano F(10), Marchetti S(10), Rocchi S(1)(2), Birling MC(1)(11), Avril MF(12), Poulalhon N(13), Luc T(13), Bertolotto C(1)(2). |
Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.Meehan TF(1), Conte N(1), West DB(2), Jacobsen JO(3), Mason J(1), Warren J(1), Chen CK(1), Tudose I(1), Relac M(1), Matthews P(1), Karp N(4), Santos L(5), Fiegel T(5), Ring N(5), Westerberg H(5), Greenaway S(5), Sneddon D(5), Morgan H(5), Codner GF(5), Stewart ME(5), Brown J(5), Horner N(5); International Mouse Phenotyping Consortium, Haendel M(6), Washington N(7), Mungall CJ(7), Reynolds CL(8), Gallegos J(8), Gailus-Durner V(9), Sorg T(10)(11)(12)(13), Pavlovic G(10)(11)(12)(13), Bower LR(14), Moore M(15), Morse I(16), Gao X(17), Tocchini-Valentini GP(18), Obata Y(19), Cho SY(20)(21), Seong JK(20)(22), Seavitt J(8), Beaudet AL(8), Dickinson ME(8), Herault Y(10)(11)(12)(13), Wurst W(9), de Angelis MH(9), Lloyd KCK(14), Flenniken AM(23), Nutter LMJ(23), Newbigging S(23), McKerlie C(23), Justice MJ(24), Murray SA(25), Svenson KL(25), Braun RE(25), White JK(4), Bradley A(4), Flicek P(1), Wells S(5), Skarnes WC(4), Adams DJ(4), Parkinson H(1), Mallon AM(5), Brown SDM(5), Smedley D(3). |
Dry ice is a reliable substrate for the distribution of frozen mouse spermatozoa: A multi-centric study.Raspa M(1), Guan M(2), Paoletti R(3), Montoliu L(4), Ayadi A(5), Marschall S(6); EMMA/Infrafrontier Technical Working Group, Fray M(2), Scavizzi F(7). |
Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE.Birling MC(1), Schaeffer L(1), Andre P(1), Lindner L(1), Marechal D(1), Ayadi A(1), Sorg T(1), Pavlovic G(1), Herault Y(1,)(2,)(3,)(4,)(5). |
Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors.Haziza S(1,)(2), Mohan N(1), Loe-Mie Y(2), Lepagnol-Bestel AM(2), Massou S(1), Adam MP(1), Le XL(1), Viard J(2), Plancon C(3), Daudin R(2), Koebel P(4), Dorard E(2), Rose C(2), Hsieh FJ(5), Wu CC(6), Potier B(2), Herault Y(4), Sala C(7), Corvin A(8), Allinquant B(2), Chang HC(5), Treussart F(1), Simonneau M(1,)(2,)(9). |
Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus.Iacono G(1), Benevento M(2)(3)(4), Dubos A(5), Herault Y(5), van Bokhoven H(2)(3)(4), Nadif Kasri N(2)(3)(4), Stunnenberg HG(6). |
Modeling human disease in rodents by CRISPR/Cas9 genome editing.Birling MC(1), Herault Y(2)(3)(4)(5)(6), Pavlovic G(2). |
Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition.Arbogast T(1)(2)(3)(4), Iacono G(5), Chevalier C(1)(2)(3)(4), Afinowi NO(6), Houbaert X(7), van Eede MC(8), Laliberte C(8), Birling MC(9), Linda K(10), Meziane H(9), Selloum M(9), Sorg T(9), Nadif Kasri N(10), Koolen DA(10), Stunnenberg HG(5), Henkelman RM(8), Kopanitsa M(6), Humeau Y(7), De Vries BBA(10), Herault Y(1)(2)(3)(4)(9). |
Non-invasive quantitative imaging of hepatocellular carcinoma growth in mice by micro-CT using liver-targeted iodinated nano-emulsions.Anton N(1)(2), Parlog A(3)(4)(5)(6), Bou About G(3)(4)(5)(6), Attia MF(7)(8)(9)(10), Wattenhofer-Donze M(3)(4)(5)(6), Jacobs H(3)(4)(5)(6), Goncalves I(3)(4)(5)(6), Robinet E(11), Sorg T(3)(4)(5)(6), Vandamme TF(7)(8). |
Prevalence of sexual dimorphism in mammalian phenotypic traits.Karp NA(1)(2), Mason J(3), Beaudet AL(4), Benjamini Y(5), Bower L(6), Braun RE(7), Brown SDM(8), Chesler EJ(7), Dickinson ME(9), Flenniken AM(10), Fuchs H(11), Angelis MH(11)(12)(13), Gao X(14), Guo S(14), Greenaway S(8), Heller R(5), Herault Y(15)(16)(17)(18)(19), Justice MJ(20), Kurbatova N(5), Lelliott CJ(21), Lloyd KCK(6), Mallon AM(8), Mank JE(22), Masuya H(23), McKerlie C(10)(24), Meehan TF(3), Mott RF(25), Murray SA(7), Parkinson H(3), Ramirez-Solis R(21), Santos L(8), Seavitt JR(4), Smedley D(26), Sorg T(15)(16)(17)(18)(19), Speak AO(21), Steel KP(21)(27), Svenson KL(7); International Mouse Phenotyping Consortium, Wakana S(23), West D(28), Wells S(8), Westerberg H(8), Yaacoby S(5), White JK(7)(21). |
RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents.Elhabazi K(1), Humbert JP(2), Bertin I(3), Quillet R(4), Utard V(5), Schneider S(6), Schmitt M(7), Bourguignon JJ(8), Laboureyras E(9), Ben Boujema M(10), Simonnet G(11), Ancel C(12), Simonneaux V(13), Beltramo M(14), Bucher B(15), Sorg T(16), Meziane H(17), Schneider E(18), Petit-Demouliere B(19), Ilien B(20), Bihel F(21), Simonin F(22). |
Rodent models in Down syndrome research: impact and future opportunities.Herault Y(1)(2)(3)(4)(5), Delabar JM(5)(6)(7)(8), Fisher EMC(5)(9)(10), Tybulewicz VLJ(5)(10)(11)(12), Yu E(5)(13)(14), Brault V(15)(2)(3)(4). |
Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.Sellier C(1), Buijsen RA(2), He F(3), Natla S(4), Jung L(5), Tropel P(5), Gaucherot A(5), Jacobs H(6), Meziane H(6), Vincent A(5), Champy MF(6), Sorg T(6), Pavlovic G(6), Wattenhofer-Donze M(6), Birling MC(6), Oulad-Abdelghani M(5), Eberling P(5), Ruffenach F(5), Joint M(5), Anheim M(7), Martinez-Cerdeno V(8), Tassone F(9), Willemsen R(2), Hukema RK(2), Viville S(10), Martinat C(11), Todd PK(12), Charlet-Berguerand N(13). |
2016Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes.Delepine C(1), Meziane H(2), Nectoux J(3), Opitz M(1), Smith AB(4), Ballatore C(5), Saillour Y(1), Bennaceur-Griscelli A(6), Chang Q(7), Williams EC(7), Dahan M(8), Duboin A(9), Billuart P(1), Herault Y(2), Bienvenu T(10). |
Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction.Codner GF(1), Lindner L(2), Caulder A(1), Wattenhofer-Donzé M(2), Radage A(1), Mertz A(2), Eisenmann B(2), Mianné J(2), Evans EP(1), Beechey CV(1), Fray MD(1), Birling MC(2), Hérault Y(2), Pavlovic G(3), Teboul L(4). |
Corrigendum: Domains of genome-wide gene expression dysregulation in Down's syndrome.Letourneau A, Santoni FA, Bonilla X, Sailani MR, Gonzalez D, Kind J, Chevalier C, Thurman R, Sandstrom RS, Hibaoui Y, Garieri M, Popadin K, Falconnet E, Gagnebin M, Gehrig C, Vannier A, Guipponi M, Farinelli L, Robyr D, Migliavacca E, Borel C, Deutsch S, Feki A, Stamatoyannopoulos JA, Herault Y, van Steensel B, Guigo R, Antonarakis SE. |
Counterregulation between thymic stromal lymphopoietin- and IL-23-driven immune axes shapes skin inflammation in mice with epidermal barrier defects.Li J(1), Leyva-Castillo JM(1), Hener P(1), Eisenmann A(1), Zaafouri S(2), Jonca N(2), Serre G(2), Birling MC(3), Li M(4). |
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome.Duchon A(1), Herault Y(2). |
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.Goguet-Rubio P(1), Seyran B(1), Gayte L(1), Bernex F(2), Sutter A(1), Delpech H(3), Linares LK(1), Riscal R(1), Repond C(4), Rodier G(3), Kirsh O(5), Touhami J(6), Noel J(7), Vincent C(8), Pirot N(7), Pavlovic G(9), Herault Y(9), Sitbon M(6), Pellerin L(4), Sardet C(3), Lacroix M(10), Le Cam L(10). |
Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.Shatirishvili M(1), Burk AS(2), Franz CM(3), Pace G(1), Kastilan T(1), Breuhahn K(4), Hinterseer E(5), Dierich A(6), Bakiri L(7), Wagner EF(7), Ponta H(1), Hartmann TN(5), Tanaka M(2,)(8), Orian-Rousseau V(1). |
Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability.Meziane H(1), Khelfaoui M(2), Morello N(3), Hiba B(4), Calcagno E(3), Reibel-Foisset S(5), Selloum M(1), Chelly J(6), Humeau Y(7), Riet F(1), Zanni G(8), Herault Y(1), Bienvenu T(9), Giustetto M(3), Billuart P(10). |
High-throughput discovery of novel developmental phenotypes.Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M, Murray SA. |
How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains.Combe R(1), Mudgett J(2), El Fertak L(1), Champy MF(1), Ayme-Dietrich E(3), Petit-Demoulière B(1), Sorg T(1), Herault Y(1), Madwed JB(2), Monassier L(1,)(3). |
Lymphopoiesis in transgenic mice over-expressing Artemis.Rivera-Munoz P(1,)(2), Abramowski V(1,)(2), Jacquot S(3), André P(3), Charrier S(4), Lipson-Ruffert K(5), Fischer A(2,)(6,)(7), Galy A(4), Cavazzana M(2,)(6), de Villartay JP(1,)(2). |
Multimodal imaging of a humanized orthotopic model of hepatocellular carcinoma in immunodeficient mice.Wu T(1,)(2,)(3), Heuillard E(1,)(2,)(4), Lindner V(5), Bou About G(6), Ignat M(7,)(8), Dillenseger JP(2,)(9,)(10,)(11), Anton N(2,)(12), Dalimier E(13), Gossé F(1,)(2), Fouré G(4), Blindauer F(4), Giraudeau C(4), El-Saghire H(1,)(2), Bouhadjar M(4), Calligaro C(4), Sorg T(6), Choquet P(2,)(9,)(10,)(11), Vandamme T(2,)(12), Ferrand C(14,)(15,)(16), Marescaux J(4,)(7,)(8), Baumert TF(1,)(2,)(4,)(7), Diana M(4,)(8), Pessaux P(1,)(2,)(4,)(7,)(8), Robinet E(1,)(2,)(4). |
Physiological Expression of AMPKgamma2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.Yang X(1), Mudgett J(2), Bou-About G(3), Champy MF(3), Jacobs H(3), Monassier L(4), Pavlovic G(3), Sorg T(3), Herault Y(3), Petit-Demouliere B(3), Lu K(1), Feng W(1), Wang H(5), Ma LJ(1), Askew R(2), Erion MD(1), Kelley DE(1), Myers RW(1), Li C(1), Guan HP(6). |
Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes.Arbogast T(1,)(2,)(3,)(4), Ouagazzal AM(1,)(2,)(3,)(4), Chevalier C(1,)(2,)(3,)(4), Kopanitsa M(5), Afinowi N(5), Migliavacca E(6,)(7), Cowling BS(1,)(2,)(3,)(4), Birling MC(8), Champy MF(8), Reymond A(6), Herault Y(1,)(2,)(3,)(4,)(8). |
Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.Lakisic G(1), Lebreton A(2,)(3,)(4), Pourpre R(1), Wendling O(5), Libertini E(6), Radford EJ(7,)(8), Le Guillou M(9), Champy MF(5), Wattenhofer-Donze M(5), Soubigou G(6), Ait-Si-Ali S(10), Feunteun J(9), Sorg T(5), Coppee JY(6), Ferguson-Smith AC(7), Cossart P(2,)(3,)(4), Bierne H(1). |
The cell proliferation antigen Ki-67 organises heterochromatin.Sobecki M(1)(2), Mrouj K(1)(2), Camasses A(1)(2), Parisis N(1)(2), Nicolas E(3), Lleres D(1)(2), Gerbe F(2)(4)(5), Prieto S(1)(2), Krasinska L(1)(2), David A(2)(4)(5), Eguren M(6), Birling MC(7), Urbach S(2)(4)(5)(8), Hem S(9), Dejardin J(2)(10), Malumbres M(6), Jay P(2)(4)(5), Dulic V(1)(2), Lafontaine DLj(3), Feil R(1)(2), Fisher D(1)(2). |
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.Scekic-Zahirovic J(1), Sendscheid O(2), El Oussini H(1), Jambeau M(3), Sun Y(3), Mersmann S(2), Wagner M(2), Dieterlé S(1), Sinniger J(1), Dirrig-Grosch S(1), Drenner K(3), Birling MC(4), Qiu J(5), Zhou Y(5), Li H(5), Fu XD(5), Rouaux C(1), Shelkovnikova T(6), Witting A(7), Ludolph AC(7), Kiefer F(8), Storkebaum E(9), Lagier-Tourenne C(10), Dupuis L(11). |
2015A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks.Erbs E(1), Faget L, Scherrer G, Matifas A, Filliol D, Vonesch JL, Koch M, Kessler P, Hentsch D, Birling MC, Koutsourakis M, Vasseur L, Veinante P, Kieffer BL, Massotte D. |
An Early Postnatal Oxytocin Treatment Prevents Social and Learning Deficits in Adult Mice Deficient for Magel2, a Gene Involved in Prader-Willi Syndrome and Autism.Meziane H(1), Schaller F(2), Bauer S(2), Villard C(3), Matarazzo V(2), Riet F(1), Guillon G(4), Lafitte D(3), Desarmenien MG(4), Tauber M(5), Muscatelli F(6). |
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.Hrabe de Angelis M, Nicholson G, Selloum M, White JK, Morgan H, Ramirez-Solis R, Sorg T, Wells S, Fuchs H, Fray M, Adams DJ, Adams NC, Adler T, Aguilar-Pimentel A, Ali-Hadji D, Amann G, AndrE P, Atkins S, Auburtin A, Ayadi A, Becker J, Becker L, Bedu E, Bekeredjian R, Birling MC, Blake A, Bottomley J, Bowl MR, Brault V, Busch DH, Bussell JN, Calzada-Wack J, Cater H, Champy MF, Charles P, Chevalier C, Chiani F, Codner GF, Combe R, Cox R, Dalloneau E, Dierich A, Di Fenza A, Doe B, Duchon A, Eickelberg O, Esapa CT, Fertak LE, Feigel T, Emelyanova I, Estabel J, Favor J, Flenniken A, Gambadoro A, Garrett L, Gates H, Gerdin AK, Gkoutos G, Greenaway S, Glasl L, Goetz P, Da Cruz IG, Gotz A, Graw J, Guimond A, Hans W, Hicks G, Holter SM, Hofler H, Hancock JM, Hoehndorf R, Hough T, Houghton R, Hurt A, Ivandic B, Jacobs H, Jacquot S, Jones N, Karp NA, Katus HA, Kitchen S, Klein-Rodewald T, Klingenspor M, Klopstock T, Lalanne V, Leblanc S, Lengger C, le Marchand E, Ludwig T, Lux A, McKerlie C, Maier H, Mandel JL, Marschall S, Mark M, Melvin DG, Meziane H, Micklich K, Mittelhauser C, Monassier L, Moulaert D, Muller S, Naton B, Neff F, Nolan PM, Nutter LM, Ollert M, Pavlovic G, Pellegata NS, Peter E, Petit-Demouliere B, Pickard A, Podrini C, Potter P, Pouilly L, Puk O, Richardson D, Rousseau S, Quintanilla-Fend L, Quwailid MM, Racz I, Rathkolb B, Riet F, Rossant J, Roux M, Rozman J, Ryder E, Salisbury J, Santos L, Schable KH, Schiller E, Schrewe A, Schulz H, Steinkamp R, Simon M, Stewart M, Stoger C, Stoger T, Sun M, Sunter D, Teboul L, Tilly I, Tocchini-Valentini GP, Tost M, Treise I, Vasseur L, Velot E, Vogt-Weisenhorn D, Wagner C, Walling A, Wattenhofer-Donze M, Weber B, Wendling O, Westerberg H, Willershauser M, Wolf E, Wolter A, Wood J, Wurst W, Yildirim AO, Zeh R, Zimmer A, Zimprich A; EUMODIC Consortium, Holmes C, Steel KP, Herault Y, Gailus-Durner V, Mallon AM, Brown SD. |
Applying the ARRIVE Guidelines to an In Vivo Database.Karp NA(1), Meehan TF(2), Morgan H(3), Mason JC(2), Blake A(3), Kurbatova N(2), Smedley D(1), Jacobsen J(1), Mott RF(4), Iyer V(5), Matthews P(5), Melvin DG(1), Wells S(3), Flenniken AM(6), Masuya H(7), Wakana S(7), White JK(8), Lloyd KC(9), Reynolds CL(10), Paylor R(11), West DB(12), Svenson KL(13), Chesler EJ(13), de Angelis MH(14), Tocchini-Valentini GP(15), Sorg T(16), Herault Y(16), Parkinson H(2), Mallon AM(3), Brown SD(3). |
Blastocyst genotyping for quality control of mouse mutant archives: an ethical and economical approach.Scavizzi F(1), Ryder E(2), Newman S(2), Raspa M(1), Gleeson D(2), Wardle-Jones H(2), Montoliu L(3,)(4), Fernandez A(3,)(4), Dessain ML(5), Larrigaldie V(5), Khorshidi Z(6), Vuolteenaho R(7), Soininen R(7), André P(8), Jacquot S(8), Hong Y(9), de Angelis MH(9), Ramirez-Solis R(2), Doe B(10). |
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.Dubos A(1), Castells-Nobau A(2), Meziane H(3), Oortveld MA(2), Houbaert X(4), Iacono G(5), Martin C(4), Mittelhaeuser C(3), Lalanne V(3), Kramer JM(2), Bhukel A(6), Quentin C(7), Slabbert J(8), Verstreken P(8), Sigrist SJ(7), Messaddeq N(9), Birling MC(3), Selloum M(3), Stunnenberg HG(5), Humeau Y(4), Schenck A(10), Herault Y(11). |
Contribution of serotonin to cardiac remodeling associated with hypertensive diastolic ventricular dysfunction in rats.Ayme-Dietrich E(1), Marzak H, Lawson R, Mokni W, Wendling O, Combe R, Becker J, El Fertak L, Champy MF, Matz R, Andriantsitohaina R, Doly S, Boutourlinsky K, Maroteaux L, Monassier L. |
Deletion of the App-Runx1 region in mice models human partial monosomy 21.Arbogast T(1), Raveau M(1), Chevalier C(1), Nalesso V(1), Dembele D(1), Jacobs H(2), Wendling O(2), Roux M(3), Duchon A(1), Herault Y(4). |
INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community.INFRAFRONTIER Consortium. |
LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.Hussein MA(1), Shrestha E(1), Ouimet M(2), Barrett TJ(2), Leone S(1), Moore KJ(2), Herault Y(3), Fisher EA(2), Garabedian MJ(1). |
Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.Brault V(1), Duchon A(1), Romestaing C(2), Sahun I(3), Pothion S(4), Karout M(1), Borel C(5), Dembele D(1), Bizot JC(6), Messaddeq N(1), Sharp AJ(7), Roussel D(2), Antonarakis SE(8), Dierssen M(3), Herault Y(9). |
Principles and application of LIMS in mouse clinics.Maier H(1), Schutt C(2), Steinkamp R(2), Hurt A(2), Schneltzer E(2), Gormanns P(2), Lengger C(2), Griffiths M(3), Melvin D(3), Agrawal N(3), Alcantara R(3), Evans A(3), Gannon D(3), Holroyd S(3), Kipp C(3), Raj NP(3), Richardson D(3), LeBlanc S(4), Vasseur L(4), Masuya H(5), Kobayashi K(5), Suzuki T(5), Tanaka N(5), Wakana S(5), Walling A(6), Clary D(7), Gallegos J(8), Fuchs H(2), de Angelis MH(9,)(10,)(11), Gailus-Durner V(2). |
Shifting eating to the circadian rest phase misaligns the peripheral clocks with the master SCN clock and leads to a metabolic syndrome.Mukherji A(1), Kobiita A(1), Damara M(1), Misra N(1), Meziane H(2), Champy MF(2), Chambon P(3). |
2014Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.Mouton-Liger F(1), Sahún I(2), Collin T(3), Lopes Pereira P(4), Masini D(2), Thomas S(1), Paly E(1), Luilier S(5), Même S(6), Jouhault Q(1), Bennaï S(1), Beloeil JC(6), Bizot JC(5), Hérault Y(7), Dierssen M(2), Créau N(8). |
Generation and Use of Transgenic Mice in Drug DiscoveryGuillaume Pavlovic, Véronique Brault, Tania Sorg andYann Hérault |
Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L mice.Lopez-Delisle L(1), Pierre-Eugène C, Bloch-Gallego E, Birling MC, Duband JL, Durand E, Bourgeois T, Matrot B, Sorg T, Huerre M, Meziane H, Roux MJ, Champy MF, Gallego J, Delattre O, Janoueix-Lerosey I. |
Impact of temporal variation on design and analysis of mouse knockout phenotyping studies.Karp NA(1), Speak AO(1), White JK(1), Adams DJ(1), Hrabé de Angelis M(2), Hérault Y(3), Mott RF(4). |
Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?Koutseff A, Mittelhaeuser C, Essabri K, Auwerx J, Meziane H. |
In Vivo 9.4T MRI and1H MRS for Evaluation of Brain Structural and Metabolic Changes in the Ts65Dn Mouse Model for Down SyndromeS. Même1*, N. Joudiou1, N. Yousfi1, F. Szeremeta1, P. Lopes-Pereira2, J. C. Beloeil1,
Y. Herault2,3,4, W. Même1 |
Old spontaneously hypertensive rats gather together typical features of human chronic left-ventricular dysfunction with preserved ejection fraction.Marzak H(1), Ayme-Dietrich E, Lawson R, Mokni W, Combe R, Becker J, Fertak LE, Champy MF, Monassier L. |
Proteomic survey reveals altered energetic patterns and metabolic failure prior to retinal degeneration.Griciuc A(1), Roux MJ, Merl J, Giangrande A, Hauck SM, Aron L, Ueffing M. |
Regulator of G-protein signaling 18 controls both platelet generation and function.Delesque-Touchard N(1), Pendaries C(1), Volle-Challier C(1), Millet L(1), Salel V(1), Hervé C(1), Pflieger AM(1), Berthou-Soulie L(2), Prades C(2), Sorg T(3), Herbert JM(1), Savi P(1), Bono F(1). |
Rfx6 maintains the functional identity of adult pancreatic beta cells.Piccand J(1), Strasser P(1), Hodson DJ(2), Meunier A(1), Ye T(1), Keime C(1), Birling MC(3), Rutter GA(2), Gradwohl G(4). |
Skin progenitor cells contribute to bleomycin-induced skin fibrosis.Liu S(1), Herault Y, Pavlovic G, Leask A. |
Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.Clar J(1), Gri B(1), Calderaro J(2), Birling MC(3), Hérault Y(3), Smit GP(4), Mithieux G(1), Rajas F(1). |
2013A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Simon MM, Greenaway S, White JK, Fuchs H, Gailus-Durner V, Wells S, Sorg T, Wong K, Bedu E, Cartwright EJ, Dacquin R, Djebali S, Estabel J, Graw J, Ingham NJ, Jackson IJ, Lengeling A, Mandillo S, Marvel J, Meziane H, Preitner F, Puk O, Roux M, Adams DJ, Atkins S, Ayadi A, Becker L, Blake A, Brooker D, Cater H, Champy MF, Combe R, Danecek P, di Fenza A, Gates H, Gerdin AK, Golini E, Hancock JM, Hans W, Holter SM, Hough T, Jurdic P, Keane TM, Morgan H, Muller W, Neff F, Nicholson G, Pasche B, Roberson LA, Rozman J, Sanderson M, Santos L, Selloum M, Shannon C, Southwell A, Tocchini-Valentini GP, Vancollie VE, Westerberg H, Wurst W, Zi M, Yalcin B, Ramirez-Solis R, Steel KP, Mallon AM, de Angelis MH, Herault Y, Brown SD. |
A pathway for unicellular tube extension depending on the lymphatic vessel determinant Prox1 and on osmoregulation.Kolotuev I(1), Hyenne V, Schwab Y, Rodriguez D, Labouesse M. |
Distinct fibroblast lineages determine dermal architecture in skin development and repair.Driskell RR(1), Lichtenberger BM(2), Hoste E(3), Kretzschmar K(2), Simons BD(4), Charalambous M(5), Ferron SR(5), Herault Y(6), Pavlovic G(6), Ferguson-Smith AC(5), Watt FM(7). |
Endogenous mammalian RF-amide peptides, including PrRP, kisspeptin and 26RFa, modulate nociception and morphine analgesia via NPFF receptors.Elhabazi K, Humbert JP, Bertin I, Schmitt M, Bihel F, Bourguignon JJ, Bucher B, Becker JA, Sorg T, Meziane H, Petit-Demoulière B, Ilien B, Simonin F. |
FELASA guidelines for the refinement of methods for genotyping genetically-modified rodents: a report of the Federation of European Laboratory Animal Science Associations Working Group.Bonaparte D(1), Cinelli P, Douni E, Hérault Y, Maas M, Pakarinen P, Poutanen M, Lafuente MS, Scavizzi F; Federation of European Laboratory Animal Science Associations Working Group. |
Repression of Osteoblast Maturation by ERR Accounts for Bone Loss Induced by Estrogen Deficiency.Gallet M, Saïdi S, Haÿ E, Photsavang J, Marty C, Sailland J, Carnesecchi J, Tribollet V, Barenton B, Forcet C, Birling MC, Sorg T, Chassande O, Cohen-Solal M, Vanacker JM. |
Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media.Bhutta MF, Cheeseman MT, Herault Y, Yu YE, Brown SD. |
The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord.Meziane H, Fraulob V, Riet F, Krezel W, Selloum M, Geffarth M, Acampora D, Hérault Y, Simeone A, Brand M, Dollé P, Rhinn M. |
The STRA6 Receptor Is Essential for Retinol-binding Protein-induced Insulin Resistance but Not for Maintaining Vitamin A Homeostasis in Tissues Other Than the Eye.Berry DC, Jacobs H, Marwarha G, Gely-Pernot A, O'Byrne SM, Desantis D, Klopfenstein M, Feret B, Dennefeld C, Blaner WS, Croniger CM, Mark M, Noy N, Ghyselinck NB. |
2012Absence of TI-VAMP/Vamp7 leads to increased anxiety in mice.Danglot L, Zylbersztejn K, Petkovic M, Gauberti M, Meziane H, Combe R, Champy MF, Birling MC, Pavlovic G, Bizot JC, Trovero F, Della Ragione F, Proux-Gillardeaux V, Sorg T, Vivien D, D'Esposito M, Galli T. |
Acoustic Startle Reflex and Prepulse Inhibition.Ouagazzal AM(1), Meziane H(2). |
Activation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists.Ces A, Reiss D, Walter O, Wichmann J, Prinssen EP, Kieffer BL, Ouagazzal AM. |
Estrogen dependent activation function of ER is essential for the sexual behavior of mouse females.Antal MC, Petit-Demoulière B, Meziane H, Chambon P, Krust A. |
Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background.Birling MC, Dierich A, Jacquot S, Hérault Y, Pavlovic G. |
Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments.Elhabazi K, Trigo JM, Mollereau C, Moulédous L, Zajac JM, Bihel F, Schmitt M, Bourguignon JJ, Meziane H, Petit-demoulière B, Bockel F, Maldonado R, Simonin F. |
Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project.Ayadi A, Birling MC, Bottomley J, Bussell J, Fuchs H, Fray M, Gailus-Durner V, Greenaway S, Houghton R, Karp N, Leblanc S, Lengger C, Maier H, Mallon AM, Marschall S, Melvin D, Morgan H, Pavlovic G, Ryder E, Skarnes WC, Selloum M, Ramirez-Solis R, Sorg T, Teboul L, Vasseur L, Walling A, Weaver T, Wells S, White JK, Bradley A, Adams DJ, Steel KP, Hrab? de Angelis M, Brown SD, Herault Y. |
Targeted ultramicrotomy: a valuable tool for correlated light and electron microscopy of small model organisms.Kolotuev I(1), Bumbarger DJ, Labouesse M, Schwab Y. |
The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.Raveau M(1), Lignon JM, Nalesso V, Duchon A, Groner Y, Sharp AJ, Dembele D, Brault V, Herault Y. |
The mammalian gene function resource: the International Knockout Mouse Consortium.Bradley A(1), Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Burger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Herault Y, Hicks G, Horlein A, Houghton R, Hrabe de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnutgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W. |
The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled.Glasco DM(1), Sittaramane V, Bryant W, Fritzsch B, Sawant A, Paudyal A, Stewart M, Andre P, Cadete Vilhais-Neto G, Yang Y, Song MR, Murdoch JN, Chandrasekhar A. |
2011Characterization and Validation of Cre-Driver Mouse LinesGofflot F, Wendling O, Chartoire N, Birling MC, Warot X, Auwerx J |
Chronic Treatment with a Promnesiant GABA-A 5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model.Braudeau J, Dauphinot L, Duchon A, Loistron A, Dodd RH, Hérault Y, Delatour B,
Potier MC. |
Genetic and pharmacological evaluation of cathepsin s in a mouse model of asthma.Deschamps K, Cromlish W, Weicker S, Lamontagne S, Huszar SL, Gauthier JY, Mudgett JS, Guimond A, Romand R, Frossard N, Percival MD, Slipetz D, Tan CM. |
Involvement of retinol dehydrogenase 10 in embryonic patterning and rescue of its loss of function by maternal retinaldehyde treatment.Rhinn M, Schuhbaur B, Niederreither K, Dollé P. |
Mouse Breeding and Colony ManagementAyadi A, Ferrand G, Goncalves da Cruz I, Warot X |
PTBP1 Is Required for Embryonic Development before GastrulationSuckale J., Wendling O., Masjkur J., Jager M., Munster C., Anastassiadis K., Stewart A.F., Solimena M. |
Reduced body weight in male Tspan8-deficient mice.Champy MF, Le Voci L, Selloum M, Peterson LB, Cumiskey AM, Blom D. |
Standardized Post-Mortem Examination and Fixation Procedures for Mutant and Treated MiceAntal M.C., muller S., Wendling O, Herault Y, Mark M. |
TASK-3 as a potential antidepressant target.Gotter AL, Santarelli VP, Doran SM, Tannenbaum PL, Kraus RL, Rosahl TW, Meziane H, Montial M, Reiss DR, Wessner K, McCampbell A, Stevens J, Brunner JI, Fox SV, Uebele VN, Bayliss DA, Winrow CJ, Renger JJ. |
The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndromeDuchon A., Pothion S., Brault V., Sharp A.J., Tybulewicz V.L., Fisher E.M., Herault Y. |
TIF1beta association with HP1 is essential for post-gastrulation development, but not for Sertoli cell functions during spermatogenesisHerzog M., Wendling O., Guillou F., Chambon P., Mark M., Losson R., Cammas F. |
2010Active multilayered capsules for in vivo bone formationFacca S., Cortez C., Mendoza-Palomares C., Messadeq N., Dierich A., Johnston A.P., Mainard D., Voegel J.C., Caruso F., Benkirane-Jessel N. |
Altered lipoprotein metabolism in P2Y(13) knockout miceBlom D., Yamin T.T., Champy M.F., Selloum M., Bedu E., Carballo-Jane E., Gerckens L., Luell S., Meurer R., Chin J., Mudgett J., Puig O. |
beta-Endorphin expression in the mouse retinaGallagher S.K., Witkovsky P., Roux M.J., Low M.J., Otero-Corchon V., Hentges S.T., Vigh J. |
Contribution of gene-modified mice and rats to our understanding of the cardiovascular pharmacology of serotoninMonassier L., Laplante M.A., Ayadi T., Doly S., Maroteaux L. |
Down Syndrome: From Understanding the Neurobiology to TherapyGardiner K., Herault Y., Lott I.T., Antonarakis S.E., Reeves R.H., Dierssen M. |
Enterovirus-related activation of the cardiomyocyte mitochondrial apoptotic pathway in patients with acute myocarditis.Ventéo L, Bourlet T, Renois F, Douche-Aourik F, Mosnier JF, Maison GL, Pluot M, Pozzetto B, Andreoletti L. |
EuroPhenome: a repository for high-throughput mouse phenotyping dataMorgan H., Beck T., Blake A., Gates H., Adams N., Debouzy G., Leblanc S., Lengger C., Maier H., Melvin D., Meziane H., Richardson D., Wells S., White J., Wood J., de Angelis M.H., Brown S.D., Hancock J.M., Mallon A.M. |
Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse f2 intercrossDerry J.M., Zhong H., Molony C., Macneil D., Guhathakurta D., Zhang B., Mudgett J., Small K., El Fertak L., Guimond A., Selloum M., Zhao W., Champy M.F., Monassier L., Vogt T., Cully D., Kasarskis A., Schadt E.E. |
Murine neonatal infection provides an efficient model for congenital ocular toxoplasmosisLahmar I., Guinard M., Sauer A., Marcellin L., Abdelrahman T., Roux M., Mousli M., Moussa A., Babba H., Pfaff A.W., Candolfi E. |
Mutations in lama1 disrupt retinal vascular development and inner limiting membrane formationEdwards M.M., Mammadova-Bach E., Alpy F., Klein A., Hicks W.L., Roux M., Simon-Assmann P., Smith R.S., Orend G., Wu J., Peachey N.S., Naggert J.K., Lefebvre O., Nishina P.M. |
Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knock-in mice.Marty C, Lacout C, Martin A, Hasan S, Jacquot S, Birling MC, Vainchenker W, Villeval JL. |
Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryoMorsut L., Yan K.P., Enzo E., Aragona M., Soligo S.M., Wendling O., Mark M., Khetchoumian K., Bressan G., Chambon P., Dupont S., Losson R., Piccolo S. |
Oxidative stress in skeletal muscle stimulates early expression of Rad in a mouse model of amyotrophic lateral sclerosis.Halter B, Gonzalez de Aguilar JL, Rene F, Petri S, Fricker B, Echaniz-Laguna A, Dupuis L, Larmet Y, Loeffler JP. |
PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.Liu M, Wu G, Baysarowich J, Kavana M, Addona GH, Bierilo KK, Mudgett JS, Pavlovic G, Sitlani A, Renger JJ, Hubbard BK, Fisher TS, Zerbinatti CV. |
Retinoic acid receptor (RAR)-alpha is not critically required for mediating retinoic acid effects in the developing mouse retinaCammas L., Trensz F., Jellali A., Ghyselinck N.B., Roux M.J., Dolle P. |
The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms.Feige JN, Gerber A, Casals-Casas C, Yang Q, Winkler C, Bedu E, Bueno M, Gelman L, Auwerx J, Gonzalez FJ, Desvergne B. |
2009A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP.Meng X, Leyva ML, Jenny M, Gross I, Benosman S, Fricker B, Harlepp S, Hébraud P, Boos A, Wlosik P, Bischoff P, Sirlin C, Pfeffer M, Loeffler JP, Gaiddon C. |
Brain structures implicated in the four-plate test in naive and experienced Swiss mice using injection of diazepam and the 5-HT2A agonist DOI.Petit-Demoulière B, Massé F, Cogrel N, Hascoët M, Bourin M. |
Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouseWendling O., Bornert J.M., Chambon P., Metzger D. |
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Häring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J. |
Ppargamma2 is a key driver of longevity in the mouseArgmann C., Dobrin R., Heikkinen S., Auburtin A., Pouilly L., Cock T.A., Koutnikova H., Zhu J., Schadt E.E., Auwerx J. |
Site-specific recombinases for manipulation of the mouse genomeBirling M.C., Gofflot F., Warot X. |
The Histone Deacetylase SIRT1 Controls Male Fertility in Mice Through Regulation of Hypothalamic-Pituitary Gonadotropin SignalingKolthur-Seetharam U., Teerds K., Rooij D.G., Wendling O., McBurney M., Sassone-Corsi P., Davidson I. |
The Pro12Ala PPARgamma2 Variant Determines Metabolism at the Gene-Environment InterfaceHeikkinen S., Argmann C., Feige J.N., Koutnikova H., Champy M.F., Dali-Youcef N., Schadt E.E., Laakso M., Auwerx J. |
2008Anxiolytic-like effects of DOI microinjections into the hippocampus (but not the amygdala nor the PAG) in the mice four plates test.Masse F, Petit-Demouliere B, Dubois I, Hascoët M, Bourin M. |
Evaluation tools and animal models of peripheral neuropathies.Fricker B, Muller A, René F. |
Factors triggering abolishment of benzodiazepines effects in the Four-Plate Test--retest in mice.Petit-Demoulière B, Hascoët M, Bourin M. |
Genetic background determines metabolic phenotypes in the mouseChampy M.F., Selloum M., Zeitler V., Caradec C., Jung B., Rousseau S., Pouilly L., Sorg T., Auwerx J. |
Nociceptin receptor impairs recognition memory via interaction with NMDA receptor-dependent mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in the hippocampusGoeldner C., Reiss D., Wichmann J., Meziane H., Kieffer B.L., Ouagazzal A.M. |
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory studyMandillo S., Tucci V., Holter S.M., Meziane H., Banchaabouchi M.A., Kallnik M., Lad H.V., Nolan P.M., Ouagazzal A.M., Coghill E.L., Gale K., Golini E., Jacquot S., Krezel W., Parker A., Riet F., Schneider I., Marazziti D., Auwerx J., Brown S.D., Chambon P., Rosenthal N., Tocchini-Valentini G., Wurst W. |
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}Coste A., Louet J.F., Lagouge M., Lerin C., Antal M.C., Meziane H., Schoonjans K., Puigserver P., O'Malley B.W., Auwerx J. |
Variations in DNA elucidate molecular networks that cause diseaseChen Y., Zhu J., Lum P.Y., Yang X., Pinto S., MacNeil D.J., Zhang C., Lamb J., Edwards S., Sieberts S.K., Leonardson A., Castellini L.W., Wang S., Champy M.F., Zhang B., Emilsson V., Doss S., Ghazalpour A., Horvath S., Drake T.A., Lusis A.J., Schadt E.E. |
2007Absence of dopamine D2 receptors unmasks an inhibitory control over the brain circuitries activated by cocaineWelter M., Vallone D., Samad T.A., Meziane H., Usiello A., Borrelli E. |
Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditureDali-Youcef N., Mataki C., Coste A., Messaddeq N., Giroud S., Blanc S., Koehl C., Champy M.F., Chambon P., Fajas L., Metzger D., Schoonjans K., Auwerx J. |
Animal models of anxiety in mice.Bourin M, Petit-Demoulière B, Dhonnchadha BN, Hascöet M. |
Bone Formation Mediated by Synergy-Acting Growth Factors Embedded in a Polyelectrolyte Multilayer FilmDierich A., Le Guen E., Messaddeq N., Stoltz J.F., Netter P., Schaaf P., Voegel J.C., Benkirane-Jessel N. |
Estrous cycle effects on behavior of C57BL/6J and BALB/cByJ female mice: implications for phenotyping strategiesMeziane H., Ouagazzal A.M., Aubert L., Wietrzych M., Krezel W. |
Evaluation of glucose homeostasisHeikkinen S, Argmann CA, Champy MF, Auwerx J |
Histopathology in mouse metabolic investigationsMark M., Teletin M., Antal C., Wendling O., Auwerx J., Heikkinen S., Khetchoumian K., Argmann C.A., Dgheem M. |
IL-13 induces expression of CD36 in human monocytes through PPARgamma activationBerry A., Balard P., Coste A., Olagnier D., Lagane C., Authier H., Benoit-Vical F., Lepert J.C., Seguela J.P., Magnaval J.F., Chambon P., Metzger D., Desvergne B., Wahli W., Auwerx J., Pipy B. |
In Vivo Imaging of Farnesoid X Receptor Activity Reveals the Ileum as the Primary Bile Acid Signaling TissueHouten S.M., Volle D.H., Cummins C.L., Mangelsdorf D.J., Auwerx J. |
Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis.Fergani A, Oudart H, Gonzalez De Aguilar JL, Fricker B, René F, Hocquette JF, Meininger V, Dupuis L, Loeffler JP. |
LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel diseaseCoste A., Dubuquoy L., Barnouin R., Annicotte J.S., Magnier B., Notti M., Corazza N., Antal M.C., Metzger D., Desreumaux P., Brunner T., Auwerx J., Schoonjans K. |
LRP1 Functions as an Atheroprotective Integrator of TGFbeta and PDFG Signals in the Vascular Wall: Implications for Marfan SyndromeBoucher P., Li W.P., Matz R.L., Takayama Y., Auwerx J., Anderson R.G., Herz J. |
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytesIndra A.K., Castaneda E., Antal M.C., Jiang M., Messaddeq N., Meng X., Loehr C.V., Gariglio P., Kato S., Wahli W., Desvergne B., Metzger D., Chambon P. |
Peroxisome Proliferator-Activated Receptor-{alpha} Activation Inhibits Langerhans Cell FunctionDubrac S., Stoitzner P., Pirkebner D., Elentner A., Schoonjans K., Auwerx J., Saeland S., Hengster P., Fritsch P., Romani N., Schmuth M. |
Quantitative ultrasonic tissue characterization as a new tool for continuous monitoring of chronic liver remodelling in miceGuimond A., Teletin M., Garo E., D'Sa A., Selloum M., Champy M.F., Vonesch J.L., Monassier L. |
Studies of the Common DIO2 Thr92Ala Polymorphism and Metabolic Phenotypes in 7342 Danish White SubjectsGrarup N., Andersen M.K., Andreasen C.H., Albrechtsen A., Borch-Johnsen K., Jorgensen T., Auwerx J., Schmitz O., Hansen T., Pedersen O. |
Systematic gene expression mapping clusters nuclear receptors according to their function in the brainGofflot F., Chartoire N., Vasseur L., Heikkinen S., Dembele D., Le Merrer J., Auwerx J. |
Temporal parameters of one-trial tolerance to benzodiazepines in four-plate test-retest.Petit-Demouliere B, Bourin M. |
The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male miceVolle D.H., Duggavathi R., Magnier B.C., Houten S.M., Cummins C.L., Lobaccaro J.M., Verhoeven G., Schoonjans K., Auwerx J. |
Tissue collection for systematic phenotyping in the mouseAntal C., Teletin M., Wendling O., Dgheem M., Auwerx J., Mark M. |
[Functional genomics of the mouse: the European dynamics].Masson R, Sorg T, Warot X. |
2006A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone developmentCobb J., Dierich A., Huss-Garcia Y., Duboule D. |
Absence of the steroid receptor coactivator-3 induces B-cell lymphomaCoste A., Antal M.C., Chan S., Kastner P., Mark M., O'Malley B.W., Auwerx J. |
ACE inhibition prevents myocardial infarction-induced skeletal muscle mitochondrial dysfunction.Zoll J, Monassier L, Garnier A, N'Guessan B, Mettauer B, Veksler V, Piquard F, Ventura-Clapier R, Geny B. |
Apoptosis and differentiation commitment: novel insights revealed by gene profiling studies in mouse embryonic stem cellsDuval D., Trouillas M., Thibault C., Dembele D., Diemunsch F., Reinhardt B., Mertz A.L., Dierich A., Boeuf H. |
Auditory and visual prepulse inhibition in mice: parametric analysis and strain comparisonsAubert L., Reiss D., Ouagazzal A.M. |
Brg1 is required for murine neural stem cell maintenance and gliogenesisMatsumoto S., Banine F., Struve J., Xing R., Adams C., Liu Y., Metzger D., Chambon P., Rao M.S., Sherman L.S. |
Cardiovascular disorders: insights into in vivo cardiovascular phenotypingMonassier L, Constantinesco A |
Conditional (loxP-flanked) allele for the gene encoding the retinoic acid-synthesizing enzyme retinaldehyde dehydrogenase 2 (RALDH2)Vermot J., Garnier J.M., Dierich A., Niederreither K., Harvey R.P., Chambon P., Dolle P. |
Deletion of peroxisome proliferator-activated receptor-alpha induces an alteration of cardiac functionsLoichot C., Jesel L., Tesse A., Tabernero A., Schoonjans K., Roul G., Carpusca I., Auwerx J., Andriantsitohaina R. |
Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout miceContet C., Gaveriaux-Ruff C., Matifas A., Caradec C., Champy M.F., Kieffer B.L. |
Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner earRomand R., Kondo T., Fraulob V., Petkovich M., Dolle P., Hashino E. |
Endocrine functions of bile acidsHouten S.M., Watanabe M., Auwerx J. |
Evaluation of Energy HomeostasisArgmann CA, Champy MF, Auwerx J |
Exploration of metabolic and endocrine function in the mouseChampy MF, Argmann CA, Chambon P, Auwerx J |
Expression analysis of murine genes using in situ hybridization with radioactive and nonradioactively labeled RNA probesChotteau-Lelievre A., Dolle P., Gofflot F. |
Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis.Mark M(1), Ghyselinck NB, Chambon P. |
Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytesCalleja C., Messaddeq N., Chapellier B., Yang H., Krezel W., Li M., Metzger D., Mascrez B., Ohta K., Kagechika H., Endo Y., Mark M., Ghyselinck N.B., Chambon P. |
Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivoScherrer G., Tryoen-Toth P., Filliol D., Matifas A., Laustriat D., Cao Y.Q., Basbaum A.I., Dierich A., Vonesh J.L., Gaveriaux-Ruff C., Kieffer B.L. |
Lipid and Bile Acid AnalysisArgmann CA, Houten SM, Champy MF, Auwerx j |
Localized inflammatory skin disease following inducible ablation of I kappa B kinase 2 in murine epidermisStratis A., Pasparakis M., Markur D., Knaup R., Pofahl R., Metzger D., Chambon P., Krieg T., Haase I. |
Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62Rodriguez A., Duran A., Selloum M., Champy M.F., Diez-Guerra F.J., Flores J.M., Serrano M., Auwerx J., Diaz-Meco M.T., Moscat J. |
Mice models of hypertensionMonassier L, Combe R, El Fertak L |
Minimizing Variation Due to Genotype and EnvironmentArgmann CA, Auwerx J |
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic programLouet J.F., Coste A., Amazit L., Tannour-Louet M., Wu R.C., Tsai S.Y., Tsai M.J., Auwerx J., O'Malley B.W. |
PGC1alpha expression is controlled in skeletal muscles by PPARbeta, whose ablation results in fiber-type switching, obesity, and type 2 diabetesSchuler M., Ali F., Chambon C., Duteil D., Bornert J.M., Tardivel A., Desvergne B., Wahli W., Chambon P., Metzger D. |
Receptor protein tyrosine phosphatase gamma is a marker for pyramidal cells and sensory neurons in the nervous system and is not necessary for normal developmentLamprianou S., Vacaresse N., Suzuki Y., Meziane H., Buxbaum J.D., Schlessinger J., Harroch S. |
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alphaLagouge M., Argmann C., Gerhart-Hines Z., Meziane H., Lerin C., Daussin F., Messadeq N., Milne J., Lambert P., Elliott P., Geny B., Laakso M., Puigserver P., Auwerx J. |
Retinoic Acid Metabolism and Signaling Pathways in the Adult and Developing Mouse TestisVernet N., Dennefeld C., Rochette-Egly C., Oulad-Abdelghani M., Chambon P., Ghyselinck N.B., Mark M. |
Retinoid signaling in inner ear developmentRomand R., Dolle P., Hashino E. |
Retinoids and spermatogenesis: Lessons from mutant mice lacking the plasma retinol binding proteinGhyselinck N.B., Vernet N., Dennefeld C., Giese N., Nau H., Chambon P., Viville S., Mark M. |
Sensory defects in Necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death.Andrieu D, Meziane H, Marly F, Angelats C, Fernandez PA, Muscatelli F. |
Skin epidermis lacking the c-myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 geneOskarsson T., Essers M.A., Dubois N., Offner S., Dubey C., Roger C., Metzger D., Chambon P., Hummler E., Beard P., Trumpp A. |
Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signalingNenci A., Huth M., Funteh A., Schmidt-Supprian M., Bloch W., Metzger D., Chambon P., Rajewsky K., Krieg T., Haase I., Pasparakis M. |
Temporal regulation of Cre recombinase activity in neural stem cellsImayoshi I., Ohtsuka T., Metzger D., Chambon P., Kageyama R. |
Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitisLi M., Hener P., Zhang Z., Kato S., Metzger D., Chambon P. |
Viral-mediated temporally controlled dopamine production in a rat model of Parkinson diseaseLi X.G., Okada T., Kodera M., Nara Y., Takino N., Muramatsu C., Ikeguchi K., Urano F., Ichinose H., Metzger D., Chambon P., Nakano I., Ozawa K., Muramatsu S. |
Visceral obesity is associated with high levels of serum squalenePeltola P., Pihlajamaki J., Koutnikova H., Ruotsalainen E., Salmenniemi U., Vauhkonen I., Kainulainen S., Gylling H., Miettinen T.A., Auwerx J., Laakso M. |
2005Assessment of left ventricular perfusion, volumes, and motion in mice using pinhole gated SPECT.Constantinesco A, Choquet P, Monassier L, Israel-Jost V, Mertz L. |
Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse developmentMatt N., Schmidt C.K., Dupe V., Dennefeld C., Nau H., Chambon P., Mark M., Ghyselinck N.B. |
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant miceMartin M., Gallego-Llamas J., Ribes V., Kedinger M., Niederreither K., Chambon P., Dolle P., Gradwohl G. |
EMPReSS: standardized phenotype screens for functional annotation of the mouse genome.Brown SD, Chambon P, de Angelis MH; Eumorphia Consortium. |
Functional role of RXRs and PPARgamma in mature adipocytesMetzger D., Imai T., Jiang M., Takukawa R., Desvergne B., Wahli W., Chambon P. |
Genomewide production of multipurpose alleles for the functional analysis of the mouse genomeSchnutgen F., De-Zolt S., Van Sloun P., Hollatz M., Hansen J., Altschmied J., Seisenberger C., Ghyselinck N.B., Ruiz P., Chambon P., Wurst W., von Melchner H. |
Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infectionDharancy S., Malapel M., Perlemuter G., Roskams T., Cheng Y., Dubuquoy L., Podevin P., Conti F., Canva V., Philippe D., Gambiez L., Mathurin P., Paris J.C., Schoonjans K., Calmus Y., Pol S., Auwerx J., Desreumaux P. |
Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammationSchoonjans K., Dubuquoy L., Mebis J., Fayard E., Wendling O., Haby C., Geboes K., Auwerx J. |
Mouse phenogenomics: the fast track to "systems metabolism"Argmann C.A., Chambon P., Auwerx J. |
Peroxisome proliferator-activated receptor gamma: the more the merrier?Argmann C.A., Cock T.A., Auwerx J. |
Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cellsMatt N., Dupe V., Garnier J.M., Dennefeld C., Chambon P., Mark M., Ghyselinck N.B. |
TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermisIndra A.K., Mohan W.S., Frontini M., Scheer E., Messaddeq N., Metzger D., Tora L. |
Targeted somatic mutagenesis in the mouse epidermisMetzger D., Li M., Chambon P. |
Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouseSchuler M., Ali F., Metzger E., Chambon P., Metzger D. |
The optomotor response: a robust first-line visual screening method for mice.Abdeljalil J, Hamid M, Abdel-Mouttalib O, Stéphane R, Raymond R, Johan A, José S, Pierre C, Serge P. |
Working memory deficits in retinoid X receptor gamma-deficient miceWietrzych M., Meziane H., Sutter A., Ghyselinck N., Chapman P.F., Chambon P., Krezel W. |
2004Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivityUm S.H., Frigerio F., Watanabe M., Picard F., Joaquin M., Sticker M., Fumagalli S., Allegrini P.R., Kozma S.C., Auwerx J., Thomas G. |
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1cWatanabe M., Houten S.M., Wang L., Moschetta A., Mangelsdorf D.J., Heyman R.A., Moore D.D., Auwerx J. |
Cardiovascular and survival effects of sympatho-inhibitors in adriamycin-induced cardiomyopathy in rats.Thomas L, Bellmont S, Christen MO, La Roche B, Monassier L. |
Cre-mediated conditional gene targeting to understand liver functionsMetzger D., Chambon P |
Current mouse models for studying cardiac dysfunctions: technical and imaging aspectsMonassier L, Theodoropoulos C, Sandler R, Constantinesco A. |
Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse modelHelmlinger D., Abou-Sleymane G., Yvert G., Rousseau S., Weber C., Trottier Y., Mandel J.L., Devys D. |
Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouseSchuler M., Dierich A., Chambon P., Metzger D. |
Expression of the liver X receptor alpha and beta in embryonic and adult miceAnnicotte J.S., Schoonjans K., Auwerx J. |
Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxiaSeznec H., Simon D., Monassier L., Criqui-Filipe P., Gansmuller A., Rustin P., Koenig M., Puccio H. |
Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )miceFajas L., Annicotte J.S., Miard S., Sarruf D., Watanabe M., Auwerx J. |
Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblastsJaffre F., Callebert J., Sarre A., Etienne N., Nebigil C.G., Launay J.M., Maroteaux L., Monassier L. |
Knockout mouse models in pain researchDierich A., Kieffer B.L. |
Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cellsMascrez B., Ghyselinck N.B., Watanabe M., Annicotte J.S., Chambon P., Auwerx J., Mark M. |
LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesisFayard E., Auwerx J., Schoonjans K. |
Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1 gamma geneYan K.P., Dolle P., Mark M., Lerouge T., Wendling O., Chambon P., Losson R. |
Mouse functional genomics requires standardization of mouse handling and housing conditionsChampy M.F., Selloum M., Piard L., Zeitler V., Caradec C., Chambon P., Auwerx J. |
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproductionMark M., Yoshida-Komiya H., Gehin M., Liao L., Tsai M.J., O'Malley B.W., Chambon P., Xu J. |
Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse.Imai T, Takakuwa R, Marchand S, Dentz E, Bornert JM, Messaddeq N, Wendling O, Mark M, Desvergne B, Wahli W, Chambon P, Metzger D. |
Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harmCock T.A., Houten S.M., Auwerx J. |
PU.1 determines the self-renewal capacity of erythroid progenitor cellsBack J., Dierich A., Bronn C., Kastner P., Chan S. |
Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epitheliumMori M., Metzger D., Picaud S., Hindelang C., Simonutti M., Sahel J., Chambon P., Mark M. |
Retinoic acid signalling in the development of branchial archesMark M., Ghyselinck N.B., Chambon P. |
Synergy between LRH-1 and beta-Catenin Induces G(1) Cyclin-Mediated Cell ProliferationBotrugno O.A., Fayard E., Annicotte J.S., Haby C., Brennan T., Wendling O., Tanaka T., Kodama T., Thomas W., Auwerx J., Schoonjans K. |
The European dimension for the mouse genome mutagenesis programAuwerx J., Avner P., Baldock R., Ballabio A., Balling R., Barbacid M., Berns A., Bradley A., Brown S., Carmeliet P., Chambon P., Cox R., Davidson D., Davies K., Duboule D., Forejt J., Granucci F., Hastie N., De Angelis M.H., Jackson I., Kioussis D., Kollias G., Lathrop M., Lendahl U., Malumbres M., Von Melchner H., Muller W., Partanen J., Ricciardi-Castagnoli P., Rigby P., Rosen B., Rosenthal N., Skarnes B., Stewart A.F., Thornton J., Tocchini-Valentini G., Wagner E., Wahli W., Wurst W. |
Tissue-specific and inducible Cre-mediated recombination in the gut epitheliumEl Marjou F., Janssen K.P., Hung-Junn Chang B., Li M., Hindie V., Chan L., Louvard D., Chambon P., Metzger D., Robine S. |
2003A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouseSchnutgen F., Doerflinger N., Calleja C., Wendling O., Chambon P., Ghyselinck N.B. |
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatmentDupe V., Matt N., Garnier J.M., Chambon P., Mark M., Ghyselinck N.B. |
Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR{gamma} hypomorphic miceKoutnikova H., Cock T.A., Watanabe M., Houten S.M., Champy M.F., Dierich A., Auwerx J. |
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouseMenissier de Murcia J., Ricoul M., Tartier L., Niedergang C., Huber A., Dantzer F., Schreiber V., Ame J.C., Dierich A., LeMeur M., Sabatier L., Chambon P., de Murcia G. |
I(1) imidazoline receptors involved in cardiovascular regulation: where are we and where are we going?Bousquet P, Greney H, Bruban V, Schann S, Ehrhardt JD, Monassier L, Feldman J. |
Knockout mice as model systems for studying nm23/NDP kinase gene functions. Application to the nm23-M1 geneArnaud-Dabernat S., Bourbon P.M., Dierich A., Le Meur M., Daniel J.Y. |
Leptin: cutting the fat off the boneCock T.A., Auwerx J. |
NSD1 is essential for early post-implantation development and has a catalytically active SET domainRayasam G.V., Wendling O., Angrand P.O., Mark M., Niederreither K., Song L., Lerouge T., Hager G.L., Chambon P., Losson R. |
Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophyNebigil C.G., Jaffre F., Messaddeq N., Hickel P., Monassier L., Launay J.M., Maroteaux L. |
Pancreatic-Duodenal Homeobox 1 Regulates Expression of Liver Receptor Homolog 1 during Pancreas DevelopmentAnnicotte J.S., Fayard E., Swift G.H., Selander L., Edlund H., Tanaka T., Kodama T., Schoonjans K., Auwerx J. |
Récepteurs à la Provençale. EMBO workshop on the biology of nuclear receptors.Auwerx J., Drouin J., Laudet V. |
TAF10 (TAF(II)30) is necessary for TFIID stability and early embryogenesis in miceMohan W.S., Scheer E., Wendling O., Metzger D., Tora L. |
2002A conditional floxed (loxP-flanked) allele for the retinoic acid receptor beta (RARbeta) geneChapellier B., Mark M., Bastien J., Dierich A., LeMeur M., Chambon P., Ghyselinck N.B. |
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RARgamma) geneChapellier B., Mark M., Garnier J.M., Dierich A., Chambon P., Ghyselinck N.B. |
A Hoxa2 knockin allele that expresses EGFP upon conditional Cre- mediated recombinationPasqualetti M., Ren S.Y., Poulet M., LeMeur M., Dierich A., Rijli F.M. |
A Hoxa2 mutant conditional allele generated by Flp- and Cre-mediated recombinationRen S.Y., Pasqualetti M., Dierich A., Le Meur M., Rijli F.M. |
Evidence for synergy between alpha(2)-adrenergic and nonadrenergic mechanisms in central blood pressure regulation.Bruban V, Estato V, Schann S, Ehrhardt JD, Monassier L, Renard P, Scalbert E, Feldman J, Bousquet P. |
Liver receptor homolog 1 controls the expression of the scavenger receptor class B type ISchoonjans K., Annicotte J.S., Huby T., Botrugno O.A., Fayard E., Ueda Y., Chapman J., Auwerx J. |
Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferationPicard F., Wanatabe M., Schoonjans K., Lydon J., O'Malley B.W., Auwerx J. |
Sigma receptors: from discovery to highlights of their implications in the cardiovascular system.Monassier L, Bousquet P. |
SRC-1 and TIF2 control energy balance between white and brown adipose tissuesPicard F., Gehin M., Annicotte J., Rocchi S., Champy M.F., O'Malley B.W., Chambon P., Auwerx J. |
The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in micePendaries C., Darblade B., Rochaix P., Krust A., Chambon P., Korach K.S., Bayard F., Arnal J.F. |
The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIPGehin M., Mark M., Dennefeld C., Dierich A., Gronemeyer H., Chambon P. |
The retinoblastoma-histone deacetylase 3 complex inhibits PPARgamma and adipocyte differentiationFajas L., Egler V., Reiter R., Hansen J., Kristiansen K., Debril M.B., Miard S., Auwerx J. |
