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  • CRISPR/Cas9 in Rodents

    PHENOMIN-ICS will present

    • - its results for generating complex mouse or rat models.
    • - the actual limitations of this system for the modification of “big” genomic sequences 
    • - the crucial request of very careful validation of the lines generated by CRISPR/Cas9

    REGISTRATION

  • Technological jump !

    the ICS developed the CRISPR Mediated REarrangement (CRISMERE) strategy to generate any kind of chromosomal rearrangement to generate mice and rat trisomy 21. Read the recent Scientific Report. Read the recent publication in Scientific Report

  • Integrated approach for bone pathology

    We offer new capabilities for analysing bone dynamics including both in vivo and ex vivo analysis of trabecular and cortical bone structures by microCT. This augments our current capacities of skeletal examinations by TRAP histological stain, X-ray, DEXA scanning, and quantitative NMR.

    Contact us for help in designing your experiments on bone dynamics!

    Picture: Representative 3D volumes illustrating trabecular microarchitecture in the caudal vertebra (left) and cortical bone in the tibia (right) of Sham-operated and Ovarectomized (OVX) mice, 9 weeks after surgery.

     

  • School for Mouse Phenogenomics

    Registration open !

    -24 experts from European landscape of the mouse phenogenomics field

    -An open yet priviledged place for exchanges and discussions of major on-going works, scientific and methodological issues

    -Share knowledge and expertise, transfer new concepts and innovative methods

    -Gain crucial skills required to use as best mutant mice

    More information at https://advanced-school.phenomin.eu/

  • Advanced Histological Stainings at ICS

    ICS is proud to offer new capabilities for histological examinations, the Masson’s trichrome and the Russell-Movat pentachrome stains. 

    Both these stains are excellent means for visualizing collagen deposits (fibroses), but with the Movat’s pentachrome stain one can also differentiate elastic fibres, muscle, mucin, and fibrin.  For detailed histological examinations or high quality images for publication, consider these stains to improve your understanding and impress your colleagues. 

    Left picture: Masson trichrone staining of a heart with massive fibrosis (in blue)

    Right picture: Movat Pentachrome Phamini modification: collagen is stained by light green

  • Neuromuscular Phenotyping

    ICS is proud to offer novel assays for assessment of neuromuscular and muscular defects as part of our phenotyping. 

    Mouse Reaching and Grasping (MoRaG) assay as well as automated gait (DigiGait) analysis now complement our existing grip strength, rotorod, and beam walking assays.  Along with  isolated muscular strength assays that are coming soon, we provide excellent capabilities to assess neuromuscular and muscular defects in your animals.  

Check the status of your project research !

PHENOMIN offers a new customer portal tool to follow step by step your mouse/rat model generation.

Events

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Mar. 30, 2017 Now Special event


Apr. 03 - Apr. 07, 2017 Training course


Apr. 06 - Apr. 07, 2017 Congress


May. 04, 2017 Workshop


May. 17 - May. 19, 2017 Congress

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