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Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome.

Mouton-Liger F(1), Sahún I(2), Collin T(3), Lopes Pereira P(4), Masini D(2), Thomas S(1), Paly E(1), Luilier S(5), Même S(6), Jouhault Q(1), Bennaï S(1), Beloeil JC(6), Bizot JC(5), Hérault Y(7), Dierssen M(2), Créau N(8).
Neurobiol Dis 2014 Mar;63():92-106

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Generation and Use of Transgenic Mice in Drug Discovery

Guillaume Pavlovic, Véronique Brault, Tania Sorg andYann Hérault
Methods And Principles In Medicinal Chemistry: In Vivo Models For Drug Discovery 2014 11 AUG 2014;62(part 6):131-148

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Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L mice.

Lopez-Delisle L(1), Pierre-Eugène C, Bloch-Gallego E, Birling MC, Duband JL, Durand E, Bourgeois T, Matrot B, Sorg T, Huerre M, Meziane H, Roux MJ, Champy MF, Gallego J, Delattre O, Janoueix-Lerosey I.
Oncotarget 2014 May 15;5(9):2703-13

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Impact of temporal variation on design and analysis of mouse knockout phenotyping studies.

Karp NA(1), Speak AO(1), White JK(1), Adams DJ(1), Hrabé de Angelis M(2), Hérault Y(3), Mott RF(4).
Plos One 2014 Oct 24;9(10):e111239

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Impact of the apolipoprotein E polymorphism, age and sex on neurogenesis in mice: Pathophysiological relevance for Alzheimer's disease?

Koutseff A, Mittelhaeuser C, Essabri K, Auwerx J, Meziane H.
Brain Res 2014 Jan 13;1542():32-40

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In Vivo 9.4T MRI and1H MRS for Evaluation of Brain Structural and Metabolic Changes in the Ts65Dn Mouse Model for Down Syndrome

S. Même1*, N. Joudiou1, N. Yousfi1, F. Szeremeta1, P. Lopes-Pereira2, J. C. Beloeil1, Y. Herault2,3,4, W. Même1
World Journal Of Neuroscience 2014 2014;4():152-163

Old spontaneously hypertensive rats gather together typical features of human chronic left-ventricular dysfunction with preserved ejection fraction.

Marzak H(1), Ayme-Dietrich E, Lawson R, Mokni W, Combe R, Becker J, Fertak LE, Champy MF, Monassier L.
J Hypertens 2014 Jun;32(6):1307-16

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Proteomic survey reveals altered energetic patterns and metabolic failure prior to retinal degeneration.

Griciuc A(1), Roux MJ, Merl J, Giangrande A, Hauck SM, Aron L, Ueffing M.
J Neurosci 2014 Feb 19;34(8):2797-812

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Regulator of G-protein signaling 18 controls both platelet generation and function.

Delesque-Touchard N(1), Pendaries C(1), Volle-Challier C(1), Millet L(1), Salel V(1), Hervé C(1), Pflieger AM(1), Berthou-Soulie L(2), Prades C(2), Sorg T(3), Herbert JM(1), Savi P(1), Bono F(1).
Plos One 2014 Nov 18;9(11):e113215

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Rfx6 maintains the functional identity of adult pancreatic beta cells.

Piccand J(1), Strasser P(1), Hodson DJ(2), Meunier A(1), Ye T(1), Keime C(1), Birling MC(3), Rutter GA(2), Gradwohl G(4).
Cell Rep 2014 Dec 24;9(6):2219-32

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Skin progenitor cells contribute to bleomycin-induced skin fibrosis.

Liu S(1), Herault Y, Pavlovic G, Leask A.
Arthritis Rheumatol 2014 Mar;66(3):707-13

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Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.

Clar J(1), Gri B(1), Calderaro J(2), Birling MC(3), Hérault Y(3), Smit GP(4), Mithieux G(1), Rajas F(1).
Kidney Int 2014 Oct;86(4):747-56

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