ICS line text

About ICS

Follow ICS

Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes.

Delepine C(1), Meziane H(2), Nectoux J(3), Opitz M(1), Smith AB(4), Ballatore C(5), Saillour Y(1), Bennaceur-Griscelli A(6), Chang Q(7), Williams EC(7), Dahan M(8), Duboin A(9), Billuart P(1), Herault Y(2), Bienvenu T(10).
Hum Mol Genet 2016 Jan 1;25(1):146-57

View on PubMed

Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction.

Codner GF(1), Lindner L(2), Caulder A(1), Wattenhofer-Donzé M(2), Radage A(1), Mertz A(2), Eisenmann B(2), Mianné J(2), Evans EP(1), Beechey CV(1), Fray MD(1), Birling MC(2), Hérault Y(2), Pavlovic G(3), Teboul L(4).
Bmc Cell Biol 2016 Aug 5;17(1):30

View on PubMed

Corrigendum: Domains of genome-wide gene expression dysregulation in Down's syndrome.

Letourneau A, Santoni FA, Bonilla X, Sailani MR, Gonzalez D, Kind J, Chevalier C, Thurman R, Sandstrom RS, Hibaoui Y, Garieri M, Popadin K, Falconnet E, Gagnebin M, Gehrig C, Vannier A, Guipponi M, Farinelli L, Robyr D, Migliavacca E, Borel C, Deutsch S, Feki A, Stamatoyannopoulos JA, Herault Y, van Steensel B, Guigo R, Antonarakis SE.
Nature 2016 Mar 17;531(7594):400

View on PubMed

Counterregulation between thymic stromal lymphopoietin- and IL-23-driven immune axes shapes skin inflammation in mice with epidermal barrier defects.

Li J(1), Leyva-Castillo JM(1), Hener P(1), Eisenmann A(1), Zaafouri S(2), Jonca N(2), Serre G(2), Birling MC(3), Li M(4).
J Allergy Clin Immunol 2016 Jul;138(1):150-161

View on PubMed

DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome.

Duchon A(1), Herault Y(2).
Front Behav Neurosci 2016 Jun 3;10():104

View on PubMed

E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.

Goguet-Rubio P(1), Seyran B(1), Gayte L(1), Bernex F(2), Sutter A(1), Delpech H(3), Linares LK(1), Riscal R(1), Repond C(4), Rodier G(3), Kirsh O(5), Touhami J(6), Noel J(7), Vincent C(8), Pirot N(7), Pavlovic G(9), Herault Y(9), Sitbon M(6), Pellerin L(4), Sardet C(3), Lacroix M(10), Le Cam L(10).
Proc Natl Acad Sci U S A 2016 Sep 27;113(39):11004-9

View on PubMed

Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.

Shatirishvili M(1), Burk AS(2), Franz CM(3), Pace G(1), Kastilan T(1), Breuhahn K(4), Hinterseer E(5), Dierich A(6), Bakiri L(7), Wagner EF(7), Ponta H(1), Hartmann TN(5), Tanaka M(2,)(8), Orian-Rousseau V(1).
Cell Death Dis 2016 Nov 10;7(11):e2461

View on PubMed

Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability.

Meziane H(1), Khelfaoui M(2), Morello N(3), Hiba B(4), Calcagno E(3), Reibel-Foisset S(5), Selloum M(1), Chelly J(6), Humeau Y(7), Riet F(1), Zanni G(8), Herault Y(1), Bienvenu T(9), Giustetto M(3), Billuart P(10).
Hum Mol Genet 2016 Jun 1;25(11):2314-2323

View on PubMed

High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bucan M, Murray SA.
Nature 2016 Sep 22;537(7621):508-514

View on PubMed

How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains.

Combe R(1), Mudgett J(2), El Fertak L(1), Champy MF(1), Ayme-Dietrich E(3), Petit-Demoulière B(1), Sorg T(1), Herault Y(1), Madwed JB(2), Monassier L(1,)(3).
Plos One 2016 Apr 18;11(4):e0153472

View on PubMed

Lymphopoiesis in transgenic mice over-expressing Artemis.

Rivera-Munoz P(1,)(2), Abramowski V(1,)(2), Jacquot S(3), André P(3), Charrier S(4), Lipson-Ruffert K(5), Fischer A(2,)(6,)(7), Galy A(4), Cavazzana M(2,)(6), de Villartay JP(1,)(2).
Gene Ther 2016 Feb;23(2):176-86

View on PubMed

Multimodal imaging of a humanized orthotopic model of hepatocellular carcinoma in immunodeficient mice.

Wu T(1,)(2,)(3), Heuillard E(1,)(2,)(4), Lindner V(5), Bou About G(6), Ignat M(7,)(8), Dillenseger JP(2,)(9,)(10,)(11), Anton N(2,)(12), Dalimier E(13), Gossé F(1,)(2), Fouré G(4), Blindauer F(4), Giraudeau C(4), El-Saghire H(1,)(2), Bouhadjar M(4), Calligaro C(4), Sorg T(6), Choquet P(2,)(9,)(10,)(11), Vandamme T(2,)(12), Ferrand C(14,)(15,)(16), Marescaux J(4,)(7,)(8), Baumert TF(1,)(2,)(4,)(7), Diana M(4,)(8), Pessaux P(1,)(2,)(4,)(7,)(8), Robinet E(1,)(2,)(4).
Sci Rep 2016 Oct 14;6():35230

View on PubMed

Physiological Expression of AMPKgamma2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.

Yang X(1), Mudgett J(2), Bou-About G(3), Champy MF(3), Jacobs H(3), Monassier L(4), Pavlovic G(3), Sorg T(3), Herault Y(3), Petit-Demouliere B(3), Lu K(1), Feng W(1), Wang H(5), Ma LJ(1), Askew R(2), Erion MD(1), Kelley DE(1), Myers RW(1), Li C(1), Guan HP(6).
J Biol Chem 2016 Nov 4;291(45):23428-23439

View on PubMed

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes.

Arbogast T(1,)(2,)(3,)(4), Ouagazzal AM(1,)(2,)(3,)(4), Chevalier C(1,)(2,)(3,)(4), Kopanitsa M(5), Afinowi N(5), Migliavacca E(6,)(7), Cowling BS(1,)(2,)(3,)(4), Birling MC(8), Champy MF(8), Reymond A(6), Herault Y(1,)(2,)(3,)(4,)(8).
Plos Genet 2016 Feb 12;12(2):e1005709

View on PubMed

Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism.

Lakisic G(1), Lebreton A(2,)(3,)(4), Pourpre R(1), Wendling O(5), Libertini E(6), Radford EJ(7,)(8), Le Guillou M(9), Champy MF(5), Wattenhofer-Donze M(5), Soubigou G(6), Ait-Si-Ali S(10), Feunteun J(9), Sorg T(5), Coppee JY(6), Ferguson-Smith AC(7), Cossart P(2,)(3,)(4), Bierne H(1).
Plos Genet 2016 Mar 3;12(3):e1005898

View on PubMed

The cell proliferation antigen Ki-67 organises heterochromatin.

Sobecki M(1)(2), Mrouj K(1)(2), Camasses A(1)(2), Parisis N(1)(2), Nicolas E(3), Lleres D(1)(2), Gerbe F(2)(4)(5), Prieto S(1)(2), Krasinska L(1)(2), David A(2)(4)(5), Eguren M(6), Birling MC(7), Urbach S(2)(4)(5)(8), Hem S(9), Dejardin J(2)(10), Malumbres M(6), Jay P(2)(4)(5), Dulic V(1)(2), Lafontaine DLj(3), Feil R(1)(2), Fisher D(1)(2).
Elife 2016 Mar 7;5():e13722

View on PubMed

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.

Scekic-Zahirovic J(1), Sendscheid O(2), El Oussini H(1), Jambeau M(3), Sun Y(3), Mersmann S(2), Wagner M(2), Dieterlé S(1), Sinniger J(1), Dirrig-Grosch S(1), Drenner K(3), Birling MC(4), Qiu J(5), Zhou Y(5), Li H(5), Fu XD(5), Rouaux C(1), Shelkovnikova T(6), Witting A(7), Ludolph AC(7), Kiefer F(8), Storkebaum E(9), Lagier-Tourenne C(10), Dupuis L(11).
Embo J 2016 Mar 7;35(10):1077-1097

View on PubMed

search icon