It is now well recognized that the microbiota plays an important role in the development, immunity and physiology of its mammalian host. Considerable progress has been made in identifying microbes and microbial metabolites that modulate host functions, maintain health or drive pathology. This knowledge has been derived from the characterization of microbiota during development and adult life, during health and disease, using animal and mechanical models to decipher the complex interactions between microbes and host, and to infer causal relationships.
The aim of this meeting is to bring together the specialists of the field to discuss novel insights into the microbiota-host mutualism and parasitism, and focus on the new models and approaches to explore this relationship.
G.Pavlovic, from PHENOMIN-ICS will present data regarding microbiota evaluation in mouse models.
In the near future, these advances will lead to the development of preventive and therapeutic strategies based on microbiota manipulation or the use of microbial metabolites, and allow the microbiota to become a key diagnostic component in precision medicine.
Gerard Eberl, Institut Pasteur
Javier Pizarro-Cerda, Institut Pasteur
Marion Berard, Institut Pasteur