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Departments

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Ovalbumin-induced asthma model

Purpose

Exploration of airway inflammation and/or airway responsiveness in ovalbumin-induced models of asthma.

Sample test results

Equipment

Advia120
Cytospin 4
Whole-body barometric plethysmograph (EMKA Technologies, Paris, France)

Recommendations

Number of animals - inflammation: 8 mice/gender/genotype
Number of animals - airway responsiveness: 12 mice/gender/genotype

HDM-induced lung inflammation

Purpose

Exploration of airway inflammation and/or airway responsiveness in House Dust Mite-induced lung inflammation.

Equipment

Advia120
Cytospin 4
Whole-body barometric plethysmograph (EMKA Technologies, Paris, France)

Recommendations

Number of animals - inflammation: 8 mice/gender/genotype

Number of animals - airway responsiveness: 12 mice/gender/genotype

Inflammation, lung inflammatory cell content in bronchoalveolar lavages (BAL) in C57BL/6N mice

Inflammation, lung inflammatory cell content in bronchoalveolar lavages (BAL) in Balb/c mice

Methacholine-induced airway responsiveness in C57BL/6N mice

Methacholine-induced airway responsiveness in Balb/c mice

LPS-induced lung inflammation

Purpose

Exploration of airway inflammation and airway responsiveness in LPS-induced inflammation model.

Strain background references

Inflammation, lung inflammatory cell content in bronchoalveolar lavages (BAL) in C57BL/6N

Spontaneous bronchospasm in LPS-induced lung inflammation model

Equipment

Advia120
Cytospin 4
Whole-body barometric plethysmograph (EMKA Technologies)

Recommendations

Number of animals - inflammation: 8 mice/gender/genotype
Number of animals - airway responsiveness: 12 mice/gender/genotype

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