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Phenotyping

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Spontaneous activity and food/water intake

Purpose

Under constant environmental conditions, mice demonstrate circadian and ultradian periodicity of activity and feeding behavior, which is driven by an endogenous clock located in suprachiasmatic nuclei in mammals. 

Measurement of spontaneous activity and food/water intake allows evaluation of biological rhythm and sleep abnormalities. 

Strain background references

Equipment

24 automated cages (Imetronic, Pessac, France).

Recommendations

10 mice per group are recommended for reliable data analysis.

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